Results 31 to 40 of about 5,124 (208)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

AUTOMATED FAULT DETECTION OF WIND TURBINE GEARBOX USING DATA- DRIVEN APPROACH

open access: yesInternational Journal of Prognostics and Health Management, 2019
Wind turbine manufacturers have adopted condition monitoring systems to monitor and report a turbine is health and operating parameters to ensure that the system operates within its design specifications.
Hemanth Mithun Praveen   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

基于粗糙集与神经网络的齿轮箱故障诊断

open access: yesJixie chuandong, 2013
A method of combining the rough sets and neural network based on the condition attributes discretization and reduct ion algorithm is proposed to fault diagnosis.
刘慧玲, 潘宏侠, 王爱玉
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Transparent exploration technology for hidden disaster-causing factors of geological structure:taking Tunbao Coal Mine in Xinjiang as an example

open access: yesMeitan kexue jishu
Hidden disaster-causing factors in coal mines are key geological factors that restrict the safety, high efficiency, green and intelligent mining, and transparent geology is an important technical means to realize the detection of hidden disaster-causing ...
Haijun WANG   +7 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

An Operational Status Assessment Model for SF6 High-Voltage Circuit Breakers Based on IAR-BTR

open access: yesSensors
With the rapid advancement of digitalization and intelligence in power systems, SF6 high-voltage circuit breakers, as the core switching devices in power grid protection systems, have become critical components in high-voltage networks of 110 kV and ...
Ningfang Wang   +4 more
doaj   +1 more source

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