Results 51 to 60 of about 178,870 (238)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
AUTOMATED FAULT DETECTION OF WIND TURBINE GEARBOX USING DATA- DRIVEN APPROACH
Wind turbine manufacturers have adopted condition monitoring systems to monitor and report a turbine is health and operating parameters to ensure that the system operates within its design specifications.
Hemanth Mithun Praveen +2 more
doaj +1 more source
Reliability analysis of dynamic systems by translating temporal fault trees into Bayesian networks [PDF]
Classical combinatorial fault trees can be used to assess combinations of failures but are unable to capture sequences of faults, which are important in complex dynamic systems.
A. Bobbio +9 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Selection of sensors by a new methodology coupling a classification technique and entropy criteria [PDF]
Complex industrial processes invest a lot of money in sensors and automation devices to monitor and supervise the process in order to guarantee the production quality and the plant and operators safety.
Cabassud, Michel +6 more
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A method of combining the rough sets and neural network based on the condition attributes discretization and reduct ion algorithm is proposed to fault diagnosis.
刘慧玲, 潘宏侠, 王爱玉
doaj
Hidden disaster-causing factors in coal mines are key geological factors that restrict the safety, high efficiency, green and intelligent mining, and transparent geology is an important technical means to realize the detection of hidden disaster-causing ...
Haijun WANG +7 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Software component testing : a standard and the effectiveness of techniques [PDF]
This portfolio comprises two projects linked by the theme of software component testing, which is also often referred to as module or unit testing. One project covers its standardisation, while the other considers the analysis and evaluation of the ...
Reid, Stuart Christopher
core +1 more source

