Results 41 to 50 of about 178,870 (238)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 2010 Recently, applying the novel data mining techniques for evaluating enterprise financial distress has received much research alternation. Support Vector Machine (SVM) and back propagation neural (BPN) network has been applied successfully in many areas ...
Lee, Ming-Chang, To, Chang
core +1 more source
A synthesis of logic and bio-inspired techniques in the design of dependable systems [PDF]
, 2016 Much of the development of model-based design and dependability analysis in the design of dependable systems, including software intensive systems, can be attributed to the application of advances in formal logic and its application to fault forecasting ...
Azevedo, Luis +7 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Design of a Highly Dependable Beamforming Chip [PDF]
, 2009 As CMOS process technology advances towards 32nm, SoC complexity continuously grows but its dependability significantly decreases. In this paper, a beamforming chip is designed using 64 reconfigurable Xentium tile processors.
Kerkhoff, H.G., Zhang, X.
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Methodology for selection of attributes and operating conditions for SVM-Based fault locator's
Tecnura, 2017 Context: Energy distribution companies must employ strategies to meet their timely and high quality service, and fault-locating techniques represent and agile alternative for restoring the electric service in the power distribution due to the size of distribution services (generally large) and the usual interruptions in the service.
Debbie Johan Arredondo Arteaga +2 more
openaire +1 more source
, 2014 Detecting faults in electrical power grids is of paramount importance, either from the electricity operator and consumer viewpoints. Modern electric power grids (smart grids) are equipped with smart sensors that allow to gather real-time information ...
De Santis, Enrico +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source