Results 61 to 70 of about 3,519,795 (189)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Transparent exploration technology for hidden disaster-causing factors of geological structure：taking Tunbao Coal Mine in Xinjiang as an example

Meitan kexue jishu
Hidden disaster-causing factors in coal mines are key geological factors that restrict the safety, high efficiency, green and intelligent mining, and transparent geology is an important technical means to realize the detection of hidden disaster-causing ...
Haijun WANG, Sanlong ZHENG, Xiangye WANG, Mintao DONG, Yan WU, Liang MA, Wei YANG, Yuying ZHU   +7 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Optimization-enhanced machine failure classification using critical sensor features and hybrid learning models with advanced optimization techniques

Scientific Reports
Industrial machine failures pose a significant challenge in modern manufacturing, leading to unexpected interruptions, increased maintenance costs, and reduced equipment reliability.
Jinqin Tang, Junling Chai, Jinkun Dai, Jicheng Feng, Ruiqing Tian, Jijing Mei, Liangxiu Zhang   +6 more
doaj   +1 more source

An Operational Status Assessment Model for SF₆ High-Voltage Circuit Breakers Based on IAR-BTR

Sensors
With the rapid advancement of digitalization and intelligence in power systems, SF6 high-voltage circuit breakers, as the core switching devices in power grid protection systems, have become critical components in high-voltage networks of 110 kV and ...
Ningfang Wang, Yujia Wang, Yifei Zhang, Ci Tang, Chenhao Sun   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Casualty Analysis of the Drivers in Traffic Accidents in Turkey: A CHAID Decision Tree Model

Applied Sciences
The number of traffic accidents in a region rises as the vehicle–km value in traffic increases. Furthermore, since automobiles make up the highest proportion of vehicles in traffic, they represent the greatest weight in traffic accidents. This study aims
Zeliha Cagla Kuyumcu, Hakan Aslan, Nilufer Yurtay   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A change-detection algorithm for short-circuit fault detection in closed-loop AC drives [PDF]

, 2013
This paper deals with an on-line method for turn-to-turn short-circuit fault detection in low-voltage permanent-magnet synchronous machine drives. Due to the closed-loop control, the fault effects are reflected in the voltage.
Johan Gyselinck, Gyselinck, Johan, KESTELYN, Xavier, Semail, Eric, Eric Semail, Yves Mollet, Meinguet, Fabien, Kestelyn, X., Mollet, Yves, Fabien Meinguet, Xavier Kestelyn   +10 more
core   +1 more source