Results 71 to 80 of about 792,011 (298)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Fault distance estimation-based protection scheme for DC microgrids
The Journal of Engineering, 2019 The DC microgrid has become a typical distribution network due to its excellent performances. However, a well-designed protection scheme still remains to be a challenge for DC microgrids.
Lin Zhang +3 more
doaj +1 more source
Superconducting fault current limiter application in a power-dense marine electrical system [PDF]
, 2011 Power-dense, low-voltage marine electrical systems have the potential for extremely high fault currents. Superconducting fault current limiters (SFCLs) have been of interest for many years and offer an effective method for reducing fault currents.
Blair, Steven Macpherson +5 more
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
IEEE AccessHybrid circuit breakers (HCBs) represent a new generation of circuit breakers that combine the advantages of mechanical breakers (MBs) and solid-state circuit breakers (SSCBs), offering fast interruption speeds and low on-state losses without requiring ...
Waqas Ali, Ara Bissal, Martin Maerz
doaj +1 more source
Motor current signal analysis using a modified bispectrum for machine fault diagnosis [PDF]
, 2009 This paper presents the use of the induction motor current to identify and quantify common faults within a two-stage reciprocating compressor. The theoretical basis is studied to understand current signal characteristics when the motor undertakes a ...
Ball, A +4 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
IEEE AccessDecaying DC offset frequently emerges as a major issue in power systems, especially under fault conditions. This leads to a distortion in the current waveform associated with the fault, which could significantly challenge protective and control ...
Mohanraj Bellie Subramani +3 more
doaj +1 more source
A Fault-Tolerant T-Type Multilevel Inverter Topology with Soft-Switching Capability Based on Si and SiC Hybrid Phase Legs [PDF]
, 2016 The performance of a novel three-phase four-leg fault-tolerant T-Type inverter topology is presented in this paper, which significantly improves the inverter\u27s fault-tolerant capability regarding device switch faults.
Demerdash, Nabeel +4 more
core +1 more source