Results 91 to 100 of about 55,562 (265)

Design of a multifunction novel flexible fault current limiter for AC distribution network. [PDF]

PLoS One, 2021
Liu Y, Guan L, Tan Z, Yang K, Guo F, Chen Y, Liu R, Zheng F.   +7 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Research on the Adaptive Protection Method for Distribution Networks With Inverter‐Type Distributed Power Supplies: Based on Short‐Circuit Impedance Calculation

Engineering Reports
In order to solve the problem of the influence of large‐scale inverter distributed power supply access to the distribution network on the reliability of distance and current protection of the traditional distribution network, an adaptive protection ...
Zhuoran Song, Zhanjun Li, Yongji Tong, Wenlei Dou, Hongbo Zhu, Tao Jiang   +5 more
doaj   +1 more source

An adaptive zero-sequence current protection scheme for distribution networks based on iterative fault current calculation of IIDGs

Zhejiang dianli
Due to the inherent output fluctuations of inverter-interfaced distributed generators （IIDGs）， the fault characteristics of distribution networks have changed， posing challenges for relay protection setting.
LI Juan, JIANG Yunlong, ZHU Rui, YANG Xiong   +3 more
doaj   +1 more source

A fast fault current calculation method for distribution networks connected with inverter interfaced distributed generators. [PDF]

MethodsX, 2021
Li Y, Wang D.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Optimum Placement of Distribution Generation Units in Power System with Fault Current Limiters Using Improved Coyote Optimization Algorithm. [PDF]

Entropy (Basel), 2021
Alghamdi H.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Adaptive DDL Algorithm to Elucidate the Protection Misoperation in Malaysian Rapid Rail DC Traction System

IEEE Access
In modern railway traffic systems, direct current (DC) electrification is a prevalent choice, with numerous traction networks adopting a variety of voltage levels to accommodate varying load current dynamics.
Vimal Rajan Bharatha Kumar, Mohammad Lutfi Othman, Noor Izzri Abdul Wahab, Hashim Bin Hizam, Mohammad Nasir Uddin, Nima Razaei, Andrew Xavier Raj Irudayaraj, Shiva Gopalakrishnan, Tasmeea Rahman   +8 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source