Results 111 to 120 of about 12,263,286 (349)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A Hybrid DC Circuit Breaker with Fault-Current-Limiting Capability for VSC-HVDC Transmission System
Energies, 2019 The direct current circuit breakers are considered a promising option to protect the transmission line against commonly appearing line-to-ground fault.
Muhammad Ahmad, Zhixin Wang
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Fault Current Limitation in Electrical Power Networks Containing HTS Cable and HTS Fuse. [PDF]
Materials (Basel), 2022 Degtyarenko PN +5 more
europepmc +1 more source
Automatism is never a defence [PDF]
, 2014 The central aim of this article is to set out and justify the contention that automatism is never a defence, not even exceptionally. Where D is not at fault for her lack of voluntariness, the term ‘automatism’ is simply a shorthand explanation that D ...
Child, John, Reed, Alan
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Quenched Flux-Coupling Superconducting Fault Current Limiter Scheme and Its Electromagnetic Design Method. [PDF]
Materials (Basel), 2023 Yan S +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Combining finite element and reinforcement learning methods to design superconducting coils of saturated iron-core superconducting fault current limiter in the DC power system. [PDF]
PLoS One, 2023 Kim CS +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source