Results 111 to 120 of about 3,149,182 (297)

Sensor Fault Detection and Fault-Tolerant Control for Buck Converter via Affine Switched Systems

open access: yesIEEE Access, 2019
The main purpose of this paper is to study the problem of the sensor fault detection and fault-tolerant control for DC-DC buck converter via affine switched systems.
Jian Li   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

On Real-Time Fault Detection in Wind Turbines: Sensor Selection Algorithm and Detection Time Reduction Analysis

open access: yesEnergies, 2016
In this paper, we address the problem of real-time fault detection in wind turbines. Starting from a data-driven fault detection method, the contribution of this paper is twofold.
Francesc Pozo   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Inversion-based synthesis algorithm of periodic fault detection and isolation filters [PDF]

open access: yes, 2013
A numerically reliable lifting-free computational method is proposed to solve fault detection and isolation problems for periodic systems using a model matching approach.
A. Varga, Varga, Andreas
core   +1 more source

Open Fault Detection and Tolerant Control for a Five Phase Inverter Driving System

open access: yesEnergies, 2016
This paper proposes a fault detection and the improved fault-tolerant control for an open fault in the five-phase inverter driving system. The five-phase induction machine has a merit of fault-tolerant control due to its increased number of phases.
Seung-Koo Baek   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Fault detection and diagnosis method for heterogeneous wireless network based on GAN

open access: yesTongxin xuebao, 2020
Aiming at the problem that in the process of network fault detection and diagnosis,how to train the precise fault diagnosis and detection model based on small data volume,a fault diagnosis and detection algorithm based on generative adversarial networks (
Xiaorong ZHU, Peipei ZHANG
doaj   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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