Results 131 to 140 of about 81,076 (316)
Descriptor system techniques in solving H2/infinity-optimal fault detection and isolation problems
, 2012 This chapter illustrates the effectiveness of descriptor systems based algorithms in solving H2/infinity-optimal fault detection and isolation problems.
Varga, Andreas
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
A Desk-top tutorial Demonstration of Model-based Fault Detection and Diagnosis
, 2007 In this paper, a demonstration on the model-based approach for fault detection has been presented. The aim of this demo is to provide students a desk-top tool to start learning model-based approach.
Gu, Fengshou +3 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
, 2012 This chapter illustrates the effectiveness of descriptor systems based algorithms in solving H2/H-infinity optimal fault detection and isolation problems.
Varga, A
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A comparative analysis of fault detection schemes for stochastic continuous-time dynamical systems
, 2008 This paper addresses a comparative analysis of the existing schemes for fault detection in continuous-time stochastic dynamical systems. Such schemes prove to be efficient when dealing with specific types of fault functions; on the other hand, they show ...
Zufiria Zatarain, Pedro José
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
On solving non-standard H-/H2/infinity fault detection problems
, 2011 We discuss solvability issues of H-/H2/infinity optimal fault detection problems in the most general setting. A solution approach is presented which successively reduces the initial problem to simpler ones.
Glover, K., Varga, A.
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