Results 101 to 110 of about 76,915 (316)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Fault Diagnosis of Rolling Bearings using Multifractal Detrended Fluctuation Analysis and Mahalanobis Distance Criterion

, 2012
Vibrations of a defective rolling bearing often exhibit nonstationary and nonlinear characteristics which are submerged in strong noise and interference components.
Gu, Fengshou, Lin, J., Lin, Jinshan, Tian, X., Gu, F., Tian, Xiange, Chen, Q., Chen, Qian   +7 more
core  

Fault Diagnosis of Rotating Machinery Based on Wavelet Domain Denoising and Metric Distance

IEEE Access, 2019
In the monitoring process of petrochemical equipment rotating machinery, the collected large data easily lead to valuable data loss in the pre-processing process and affecting the accuracy of the fault diagnosis.
Naiquan Su, Xiao Li, Qianghua Zhang
doaj   +1 more source

Diagnosis and Fault‐tolerant Control 2

, 2021
This book presents recent advances in fault diagnosis and fault-tolerant control of dynamic processes. Its impetus derives from the need for an overview of the challenges of the fault diagnosis technique and sustainable control, especially for those demanding systems that require reliability, availability, maintainability, and safety to ensure ...
Puig V., Simani S.
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Fault severity diagnosis of rolling element bearings based on kurtogram and envelope analysis

, 2014
Faults in rolling element bearing are among the main causes of breakdown in rotating machines. Vibration is an effective technique for machine condition monitoring.
Gu, Fengshou, Chen, Zhi, Rehab, Ibrahim, Ball, Andrew, Rehab, Ibrahim.A.M, Wang, Tie, Tian, Xiange   +6 more
core  

Wind Speed Interval Prediction Based on Bayesian Optimized Spatio-Temporal Integration and Compression Deep Residual Network

Sensors
To address the challenge of high wind speed variability in wind farm planning, a small-sample-based spatio-temporal fusion and compression deep residual point prediction model, STiCDRS (Spatio-Temporal integration and Compression Deep Residual), is ...
Yun Wu, Yongzhen Gong, Xiaoguo Chen, Xingang Wang, Xiaoyong Li   +4 more
doaj   +1 more source

Task Data Offloading and Resource Allocation in Fog Computing With Multi-Task Delay Guarantee

IEEE Access, 2019
With the emergence of delay-sensitive task completion, computational offloading becomes increasingly desirable due to the end-user's limitations in performing computation-intense applications. Interestingly, fog computing enables computational offloading
Mithun Mukherjee, Suman Kumar, Qi Zhang, Rakesh Matam, Constandinos X. Mavromoustakis, Yunrong Lv, George Mastorakis   +6 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

An Attention-Based Multidimensional Fault Information Sharing Framework for Bearing Fault Diagnosis

Deep learning has performed well in feature extraction and pattern recognition and has been widely studied in the field of fault diagnosis. However, in practical engineering applications, the lack of sample size limits the potential of deep learning in ...
Yizong Zhang, Xudong Yang, Hai Yang, Yunjin Hu, Qingsheng Xie   +4 more
core   +1 more source