Results 81 to 90 of about 244,875 (297)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Security and Privacy in Fog Computing: Challenges

open access: yesIEEE Access, 2017
Fog computing paradigm extends the storage, networking, and computing facilities of the cloud computing toward the edge of the networks while offloading the cloud data centers and reducing service latency to the end users. However, the characteristics of
Mithun Mukherjee   +6 more
doaj   +1 more source

Similarity Matching Techniques For Fault Diagnosis In Automotive Infotainment Electronics [PDF]

open access: yes, 2009
Fault diagnosis has become a very important area of research during the last decade due to the advancement of mechanical and electrical systems in industries. The automobile is a crucial field where fault diagnosis is given a special attention.
Kabir, Mashud
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Research on Convolutional Neural Network Model for Sonar IMAGE Segmentation

open access: yesMATEC Web of Conferences, 2018
The speckle noise of sonar images affects the human interpretation and automatic recognition of images seriously. It is important and difficult to realize the precision segmentation of sonar image with speckle noise in the field of image processing. Full
Jiao Shengxi, Zhao Chunyu, Xin Ye
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Expert systems for real-time monitoring and fault diagnosis [PDF]

open access: yes
Methods for building real-time onboard expert systems were investigated, and the use of expert systems technology was demonstrated in improving the performance of current real-time onboard monitoring and fault diagnosis applications.
Caglayan, A. K., Edwards, S. J.
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Fault Diagnosis of Rotating Machinery Based on Wavelet Domain Denoising and Metric Distance

open access: yesIEEE Access, 2019
In the monitoring process of petrochemical equipment rotating machinery, the collected large data easily lead to valuable data loss in the pre-processing process and affecting the accuracy of the fault diagnosis.
Naiquan Su, Xiao Li, Qianghua Zhang
doaj   +1 more source

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