Results 71 to 80 of about 244,875 (297)

Combining the Multi-Genetic Algorithm and Support Vector Machine for Fault Diagnosis of Bearings

Shock and Vibration, 2018
Overstudy or understudy phenomena can sometimes occur due to the strong dependence of support vector machine (SVM) algorithms on particular parameters and the lack of systems theory relating to parameter selection. In this paper, a parameter optimization
Jianbin Xiong, Qinghua Zhang, Qiong Liang, Hongbin Zhu, Haiying Li   +4 more
doaj   +1 more source

A Multi-Objective Optimization Scheduling Method Based on the Ant Colony Algorithm in Cloud Computing

IEEE Access, 2015
For task-scheduling problems in cloud computing, a multi-objective optimization method is proposed here. First, with an aim toward the biodiversity of resources and tasks in cloud computing, we propose a resource cost model that defines the demand of ...
Liyun Zuo, Lei Shu, Shoubin Dong, Chunsheng Zhu, Takahiro Hara   +4 more
doaj   +1 more source

Matrix converter open circuit fault behavior analysis and diagnosis with a model predictive control strategy [PDF]

, 2018
A novel fast and reliable open circuit fault diagnosis strategy for a Matrix Converter with a Finite Control Set Model Predictive Control strategy is proposed in this paper.
Dan, Hanbing, De Lillo, Liliana, Empringham, Lee, Wheeler, Patrick, Zhang, Jiawei   +4 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Multi-objective structural optimization of hub unit bearing using response surface methodology and genetic algorithm

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
Hub unit bearings are key components in automobiles for carrying load and accurate piloting. The hub unit bearing must be of a smaller size and lighter weight to meet the requirements of automobile for higher fuel efficiency, improved ease of movement ...
Xiaohui LU, Xiaopeng XIE
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Fault diagnosis with dynamic observers [PDF]

2008 9th International Workshop on Discrete Event Systems, 2008
In this paper, we review some recent results about the use of dynamic observers for fault diagnosis of discrete event systems. Fault diagnosis consists in synthesizing a diagnoser that observes a given plant and identifies faults in the plant as soon as possible after their occurrence.
Cassez, Franck, Tripakis, Stavros
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source