Results 51 to 60 of about 244,875 (297)

Case-based reasoning combined with statistics for diagnostics and prognosis [PDF]

open access: yes, 2012
Many approaches used for diagnostics today are based on a precise model. This excludes diagnostics of many complex types of machinery that cannot be modelled and simulated easily or without great effort.
Funk, Peter, Olsson, Tomas
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Geographic Routing in Duty-Cycled Industrial Wireless Sensor Networks With Radio Irregularity

open access: yesIEEE Access, 2016
Industrial wireless sensor networks (IWSNs) are required to provide highly reliable and real-time transmission. Moreover, for connected K-neighborhood (CKN) sleep scheduling-based duty-cycled IWSNs in which the network lifetime of IWSNs can be prolonged,
Lei Shu   +4 more
doaj   +1 more source

Selection of sensors by a new methodology coupling a classification technique and entropy criteria [PDF]

open access: yes, 2007
Complex industrial processes invest a lot of money in sensors and automation devices to monitor and supervise the process in order to guarantee the production quality and the plant and operators safety.
Cabassud, Michel   +6 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Bearing Fault Diagnosis Method Based on Ensemble Composite Multi-Scale Dispersion Entropy and Density Peaks Clustering

open access: yesIEEE Access, 2021
For bearing fault diagnosis, how to effectively extract informative fault information and accurately diagnose faults is still a key problem. To this end, this study proposes a novel bearing fault diagnosis approach based on ensemble composite multi-scale
Ai-Song Qin   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Modeling Fault Propagation Paths in Power Systems: A New Framework Based on Event SNP Systems With Neurotransmitter Concentration [PDF]

open access: yes, 2019
To reveal fault propagation paths is one of the most critical studies for the analysis of power system security; however, it is rather dif cult. This paper proposes a new framework for the fault propagation path modeling method of power systems based ...
Huang, Tao   +6 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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