Results 91 to 100 of about 244,875 (297)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Wind Speed Interval Prediction Based on Bayesian Optimized Spatio-Temporal Integration and Compression Deep Residual Network

open access: yesSensors
To address the challenge of high wind speed variability in wind farm planning, a small-sample-based spatio-temporal fusion and compression deep residual point prediction model, STiCDRS (Spatio-Temporal integration and Compression Deep Residual), is ...
Yun Wu   +4 more
doaj   +1 more source

Task Data Offloading and Resource Allocation in Fog Computing With Multi-Task Delay Guarantee

open access: yesIEEE Access, 2019
With the emergence of delay-sensitive task completion, computational offloading becomes increasingly desirable due to the end-user's limitations in performing computation-intense applications. Interestingly, fog computing enables computational offloading
Mithun Mukherjee   +6 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Graph-based real-time fault diagnostics [PDF]

open access: yes
A real-time fault detection and diagnosis capability is absolutely crucial in the design of large-scale space systems. Some of the existing AI-based fault diagnostic techniques like expert systems and qualitative modelling are frequently ill-suited for ...
Karsai, G.   +2 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Path-Loss-Based Fingerprint Localization Approach for Location-Based Services in Indoor Environments

open access: yesIEEE Access, 2017
Wireless local area network fingerprint-based indoor localization schemes have been widely studied because of the increasing requirements of location-based services (LBSs). The features of fingerprint based localization are known to have higher precision
Jie Zhang   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Task Allocation Algorithm Based on Score Incentive Mechanism for Wireless Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2015
A wireless sensor network (WSN) consists of many resource constraint sensor nodes, which are always deployed in unattended environment. Therefore, the sensor nodes are vulnerable to failure and malicious attacks.
Feng Wang   +4 more
doaj   +1 more source

On-line diagnosis of unrestricted faults [PDF]

open access: yes
A formal model for the study of on-line diagnosis is introduced and used to investigate the diagnosis of unrestricted faults. A fault of a system S is considered to be a transformation of S into another system S' at some time tau.
Meyer, J. F., Sundstrom, R. J.
core   +1 more source

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