Results 121 to 130 of about 297,161 (352)

A distributed fault-detection and diagnosis system using on-line parameter estimation [PDF]

open access: yes
The development of a model-based fault-detection and diagnosis system (FDD) is reviewed. The system can be used as an integral part of an intelligent control system.
Duyar, A., Guo, T.-H., Merrill, W.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Ship Track Regression Based on Support Vector Machine

open access: yesIEEE Access, 2017
This work was supported in part by the National Natural Science Foundation of China under Grant 61473331, in part by the Natural Science Foundation of Guangdong Province of China under Grant 2014A030307049, in part by the Ordinary University Innovation ...
Bo Ban   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Stability evolution mechanisms and control strategies for lower and upper trapezoidal blocks in fully mechanized top-coal caving faces of extra-thick coal seams

open access: yesFrontiers in Earth Science
In underground coal mining operations, particularly in fully mechanized top-coal caving (FMTC) faces of extra-thick coal seams, structural instability after key stratum fracturing will cause severe deformation and damage to the surrounding rock mass of ...
Binbin Qin   +11 more
doaj   +1 more source

Composite Fault Diagnosis for Rotating Machinery of Large Units Based on Evidence Theory and Multi-Information Fusion

open access: yesShock and Vibration, 2019
Due to the complexity of the structure and process of large-scale petrochemical equipment, different fault characteristics are mixed and present multiple couplings and ambiguities, leading to the difficulty in identifying composite faults in rotating ...
Naiquang Su   +3 more
doaj   +1 more source

An Adaptive Framework for Improving Quality of Service in Industrial Systems

open access: yesIEEE Access, 2015
Limited memory bandwidth is considered as the major bottleneck in multimedia cloud computing for more and more virtual machines (VMs) of multimedia processing requiring high memory bandwidth simultaneously.
Gangyong Jia   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Real Time Fault Diagnosis for Propulsion Systems [PDF]

open access: green, 1991
W. Merrill   +3 more
openalex   +1 more source

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