Results 51 to 60 of about 99,648 (313)

An Experimental Study of Clogging Fault Diagnosis in Heat Exchangers Based on Vibration Signals

open access: yesIEEE Access, 2016
The water-circulating heat exchangers employed in petrochemical industrials have attracted great attention in condition monitoring and fault diagnosis. In this paper, an approach based on vibration signals is proposed.
Jianfeng Huang   +4 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Combining the Multi-Genetic Algorithm and Support Vector Machine for Fault Diagnosis of Bearings

open access: yesShock and Vibration, 2018
Overstudy or understudy phenomena can sometimes occur due to the strong dependence of support vector machine (SVM) algorithms on particular parameters and the lack of systems theory relating to parameter selection. In this paper, a parameter optimization
Jianbin Xiong   +4 more
doaj   +1 more source

A Multi-Objective Optimization Scheduling Method Based on the Ant Colony Algorithm in Cloud Computing

open access: yesIEEE Access, 2015
For task-scheduling problems in cloud computing, a multi-objective optimization method is proposed here. First, with an aim toward the biodiversity of resources and tasks in cloud computing, we propose a resource cost model that defines the demand of ...
Liyun Zuo   +4 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Multi-objective structural optimization of hub unit bearing using response surface methodology and genetic algorithm

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
Hub unit bearings are key components in automobiles for carrying load and accurate piloting. The hub unit bearing must be of a smaller size and lighter weight to meet the requirements of automobile for higher fuel efficiency, improved ease of movement ...
Xiaohui LU, Xiaopeng XIE
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Fault diagnosis with dynamic observers [PDF]

open access: yes2008 9th International Workshop on Discrete Event Systems, 2008
In this paper, we review some recent results about the use of dynamic observers for fault diagnosis of discrete event systems. Fault diagnosis consists in synthesizing a diagnoser that observes a given plant and identifies faults in the plant as soon as possible after their occurrence.
Cassez, Franck, Tripakis, Stavros
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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