The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Adaptive fault identification for a class of nonlinear dynamic systems
This paper is concerned with the diagnosis problem of actuator faults for a class of nonlinear systems. It is assumed that the upper bound of the Lipschtiz constant of the nonlinearity in the faulty system is unknown.
Ye D(叶丹) +2 more
core
Electric Bicycle Series Arc Fault Identification Method Based on Improved PCA and SVM. [PDF]
Yang K, Chen J, Yang Z, Ma Z, Zhang R.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
A fusion sparse learning algorithm for fault identification of rolling bearings. [PDF]
Liu Y, Liu J, Ma Y, Wang S, Zhang Q.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
A Novel Fault-Identification Method for Micro Coils of EMECs Based on a Composite Analytical Model Combining a 2D Thermal Model and a 1D-CNN. [PDF]
Wang A, You J, Tan X, Xue Y, Jin X.
europepmc +1 more source
A novel intelligent fault identification method based on random forests for HVDC transmission lines. [PDF]
Wu H, Wang Q, Yu K, Hu X, Ran M.
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Natural-language-processing and safety-engineering-based fault identification technique for electrochemical ESSs. [PDF]
Li Y +14 more
europepmc +1 more source

