Results 141 to 150 of about 39,327 (311)

Fault Identification in Electric Servo Actuators of Robot Manipulators Described by Nonstationary Nonlinear Dynamic Models Using Sliding Mode Observers. [PDF]

Sensors (Basel), 2022
Zuev A, Zhirabok AN, Filaretov V, Protsenko A.   +3 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

AN ARTIFICIAL INTELLIGENCE APPROACH FOR FAULT DETECTION AND IDENTIFICATION ON CUBESAT PLATFORMS

, 2016
Algorithms involving artificial intelligence (i.e. neural networks and fuzzy logics) have begun to spread in the space applications in recent years. This has been made possible thanks to the increase of the know-how on machine-learning techniques and the
MOZZILLO, RAFFAELE, CORPINO, Sabrina, FERUGLIO, LORENZO, FRANCHI, LORIS   +3 more
core  

A transmission line fault identification method based on Deep Forest and SMOTE

Zhejiang dianli
Power transmission line faults exhibit multi-causal origins and imbalanced occurrence frequencies across fault types， resulting in significant class imbalance in transient waveform data.
JIANG Kaihua, ZHANG Yong, XIE Yingpu, LI Te, WANG Shaohua, LEI Mengfei, WANG Bowen   +6 more
doaj   +1 more source

A Novel Feature Extraction and Fault Detection Technique for the Intelligent Fault Identification of Water Pump Bearings. [PDF]

Sensors (Basel), 2021
Irfan M, Alwadie AS, Glowacz A, Awais M, Rahman S, Khan MKA, Jalalah M, Alshorman O, Caesarendra W.   +8 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Noise identification and fault diagnosis for the new products of the automobile gearbox

, 2009
A noise identification and fault diagnosis system for the new products of the automobile gearbox is introduced. The framework of the developed software is described, which includes function modules as data acquisition, feature extracting, time frequency ...
Yan YG(闫一功), Shi HB(史海波), Shang WL(尚文利)   +2 more
core  

Damage Tolerant Active Contro l: Concept and State of the Art [PDF]

, 2012
Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
NOBREGA, Euripedes, MECHBAL, Nazih
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source