Results 131 to 140 of about 409,912 (301)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Diagnosis Methodology Based on Deep Feature Learning for Fault Identification in Metallic, Hybrid and Ceramic Bearings. [PDF]

Sensors (Basel), 2021
Saucedo-Dorantes JJ, Arellano-Espitia F, Delgado-Prieto M, Osornio-Rios RA.   +3 more
europepmc   +1 more source

Applications of Fault Detection in Vibrating Structures [PDF]

Structural fault detection and identification remains an area of active research. Solutions to fault detection and identification may be based on subtle changes in the time series history of vibration signals originating from various sensor locations ...
Eure, Kenneth W., Hill, Boyd L., Hogge, Edward, Quach, Cuong C., Russell, Andrew, Vazquez, Sixto L.   +5 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

A transmission line fault identification method based on Deep Forest and SMOTE

Zhejiang dianli
Power transmission line faults exhibit multi-causal origins and imbalanced occurrence frequencies across fault types， resulting in significant class imbalance in transient waveform data.
JIANG Kaihua, ZHANG Yong, XIE Yingpu, LI Te, WANG Shaohua, LEI Mengfei, WANG Bowen   +6 more
doaj   +1 more source

Fault Identification in Electric Servo Actuators of Robot Manipulators Described by Nonstationary Nonlinear Dynamic Models Using Sliding Mode Observers. [PDF]

Sensors (Basel), 2022
Zuev A, Zhirabok AN, Filaretov V, Protsenko A.   +3 more
europepmc   +1 more source

Performance Analysis on Fault Tolerant Control System [PDF]

In a fault tolerant control (FTC) system, a parameter varying FTC law is reconfigured based on fault parameters estimated by fault detection and isolation (FDI) modules.
Belcastro, Christine, Shin, Jong-Yeob
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A Novel Feature Extraction and Fault Detection Technique for the Intelligent Fault Identification of Water Pump Bearings. [PDF]

Sensors (Basel), 2021
Irfan M, Alwadie AS, Glowacz A, Awais M, Rahman S, Khan MKA, Jalalah M, Alshorman O, Caesarendra W.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source