Results 111 to 120 of about 409,912 (301)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Research on Early Aging Fault Identification of Photovoltaic DC Combiner System
EnergiesIn order to detect typical faults in the photovoltaic Direct current (DC) system, this paper first compared and analyzed the frequency domain responses of two typical faults in the photovoltaic DC system at different insulation aging stages based on the ...
Yu Zou +4 more
doaj +1 more source
Making intelligent systems team players: Case studies and design issues. Volume 1: Human-computer interaction design [PDF]
Initial results are reported from a multi-year, interdisciplinary effort to provide guidance and assistance for designers of intelligent systems and their user interfaces.
Forbus, Kenneth D. +6 more
core +1 more source
Fault detection, identification and accommodation techniques for unmanned airborne vehicles [PDF]
, 2005 Unmanned Airborne Vehicles (UAV) are assuming prominent roles in both the commercial and military aerospace industries. The promise of reduced costs and reduced risk to human life is one of their major attractions, however these low-cost systems are yet ...
Cork, Lennon +2 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FAULT DIAGNOSIS OF PUMPING UNIT BASED ON GLOBAL AND LOCAL FEATURES
Jixie qiangdu, 2023 In order to accurately and timely judge the fault location of pumping unit and change the inefficient manual fault diagnosis mode, a fault identification method of pumping unit based on Mahalanobis Taguchi system was proposed . Firstly, the geometric and
ZHAO XinYu, FAN Jun, HE Fang, TANG LiWen
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Fault Identification in Membrane Structures Using the Hilbert Transforms. [PDF]
Sensors (Basel), 2022 Waszczuk-Młyńska A +2 more
europepmc +1 more source
A robust algebraic approach to fault diagnosis of uncertain linear systems [PDF]
, 2011 International audienceThis article proposes an algebraic method to fault diagnosis for uncertain linear systems. The main advantage of this new approach is to realize fault diagnosis only from knowledge of input and output measurements without identi ...
Hamelin, Frédéric +2 more
core +2 more sources