Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Fault Identification and Localization of a Time-Frequency Domain Joint Impedance Spectrum of Cables Based on Deep Belief Networks. [PDF]
Sensors (Basel), 2023 Wan Q, Li Y, Yuan R, Meng Q, Li X.
europepmc +1 more source
Fault Estimation Methods for Semi-Active Suspension Systems
, 2015 International audienceSemi-Active (SA) suspension systems aim to improve the stability and comfort of vehicles. Although they offer better performance than passive suspensions, the actuators such as magneto-rheological dampers are more susceptible to ...
Amezquita-Brooks, Luis +4 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A new method for fault identification of T-connection transmission line based on multi-scale traveling wave reactive power and random forest. [PDF]
PLoS One, 2023 Zhong Y, Yang J, Wang S, Deng S, Hu L.
europepmc +1 more source
Real-time diagnostics for a reusable rocket engine [PDF]
A hierarchical, decentralized diagnostic system is proposed for the Real-Time Diagnostic System component of the Intelligent Control System (ICS) for reusable rocket engines.
Duyar, A., Guo, T. H., Merrill, W.
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
A Vibration Fault Identification Framework for Shafting Systems of Hydropower Units: Nonlinear Modeling, Signal Processing, and Holographic Identification. [PDF]
Sensors (Basel), 2022 Shi Y, Zhou J, Huang J, Xu Y, Liu B.
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Gearbox Fault Identification Model Using an Adaptive Noise Canceling Technique, Heterogeneous Feature Extraction, and Distance Ratio Principal Component Analysis. [PDF]
Sensors (Basel), 2022 Nguyen CD, Kim CH, Kim JM.
europepmc +1 more source