Results 51 to 60 of about 12,124 (305)
Structural complexity is common at the terminations of earthquake surface ruptures; similar deformation may therefore be expected at the end zones of earthquake ruptures at depth.
Kirkpatrick, J. D. +14 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Effective fault localization technique using parameter-value replacement
Statistic-based fault localization and slice-based fault localization cannot locate the omission faults effectively.A method-level fault localization approach based on parameter-value replacement was proposed.Those methods appearing in failed executions ...
Xing-ya WANG +3 more
doaj +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Flow-Sensitive Fault Localization [PDF]
Identifying the cause of an error is often the most time-consuming part in program debugging. Fault localization techniques can help to automate this task. Particularly promising are static proof-based techniques that rely on an encoding of error traces into trace formulas. By identifying irrelevant portions of the trace formula, the possible causes of
Jürgen Christ +3 more
openaire +1 more source
Fault Detection of Gearbox from Inverter Signals Using Advanced Signal Processing Techniques
The gear faults are time-localized transient events so time-frequency analysis techniques (such as the Short-Time Fourier Transform, Wavelet Transform, motor current signature analysis) are widely used to deal with non-stationary and nonlinear signals ...
Gu, Fengshou +7 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Fault tolerant localization and tracking of multiple sources in WSNs using binary data
This paper investigates the use of a Wireless Sensor Network for localizing and tracking multiple event sources (targets) using only binary data.
Michaelides, Michalis P. +2 more
core +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Spectrum-based fault localization (SBFL), one of the typical types of software fault localization techniques, has been widely adopted to assist developers in identifying faulty program elements.
Wen Yao, Mingyue Jiang, Yuan Zhou
doaj +1 more source

