Results 71 to 80 of about 12,124 (305)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Fault Detection, Localization, and Tolerant Operation of Modular Multilevel Converters with an Insulated Gate Bipolar Transistor (IGBT) Open Circuit Fault

Energies, 2018
Reliability is one of the critical issues for a modular multilevel converter (MMC) since it consists of a large number of series-connected power electronics submodules (SMs).
Wei Li, Gengyin Li, Rong Zeng, Kai Ni, Yihua Hu, Huiqing Wen   +5 more
doaj   +1 more source

Automatic Fault Localization for BIP [PDF]

, 2015
This paper presents a novel idea of automatic fault localization by exploiting counterexamples generated by a model checker. The key insight is that, if a candidate statement is faulty, it is possible to modify i.e. correct this statement so that the counterexample is eliminated.
Qiang Wang 0020, Yan Lei, Simon Bliudze, Xiaoguang Mao   +3 more
openaire   +1 more source

Localization of Quaternary slip rates in an active rift in 10(5) years: an example from central Greece constrained by U-234-Th-230 coral dates from uplifted paleoshorelines

, 2009
Mapping, dating, and modeling of paleoshorelines uplifted in the footwall of the 1981 Gulf of Corinth earthquake fault, Greece (Ms 6.9–6.7), are used to assess its slip rate history relative to other normal faults in the area and study strain ...
Wigley, T., Cowie, P A, S. L. Houghton, J. M. McArthur, McArthur, J. M., Papanikolaou, I, Cooper, Frances J, T. Wigley, van Calsteren, Peter, C. Underwood, Underwood, Charlie J., Cowie, P.A., F. J. Cooper, Cooper, F.J., Roberts, Gerald P., van Calsteren, P, Houghton, S. L., McArthur, J.M., Papanikolaou, Ioannis D., Papanikolaou, I., Wigley, T, P. van Calsteren, Cowie, P. A., Houghton, S L, I. Papanikolaou, Roberts, G. P., Roberts, G P, McArthur, J M, Cooper, F. J., G. P. Roberts, P. A. Cowie, Underwood, C., Underwood, C, van Calsteren, P., Houghton, S.L.   +34 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A mixed approach to spectrum-based fault localization using information theoretic foundations

, 2014
textFault localization, i.e., locating faults in code, such as faulty statements or expressions, which are responsible for observed failures, is traditionally a manual, laborious, and tedious task.
Roychowdhury, Shounak
core  

Robust fault detection for networked systems with distributed sensors

, 2011
Copyright [2011] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Zidong Wang, He, X, Wang, Z, Xiao He, D. H. Zhou, Ji, YD, Zhou, DH, Y. D. Ji   +7 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Feature-Based Fault Localization in Evolving Software: Leveraging Regression Testing Insights

IEEE Access
Fault localization remains a vital yet resource-intensive task, particularly within software evolution, where swift and accurate fault localization is crucial.
Faeze Aghazade-Par, Mojtaba Vahidi-Asl
doaj   +1 more source

The walls boundary fault zone and the MØre TrØndelag fault complex:: a case study of two reactivated fault zones. [PDF]

, 2001
It is commonly observed that ancient faults or shear zones can become reactivated again and again, either within the same or even superimposed tectonic episodes, yet millions of years apart.
Watts, Lee Mark
core