Results 91 to 100 of about 12,124 (305)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
EnergiesMedium-voltage cables in hydropower plants are typically arranged in multi-circuit configurations to ensure reliability, yet their exposure to harsh operational conditions accelerates insulation degradation and increases partial discharge risks ...
Zhichao Li +5 more
doaj +1 more source
Fault Detection and Localization in Transmission Lines with a Static Synchronous Series Compensator
Advances in Electrical and Computer Engineering, 2015 This paper proposes a fault detection and localization method for power transmission lines with a Static Synchronous Series Compensator (SSSC). The algorithm is based on applying a modal transformation to the current and voltage signals sampled at ...
REYES-ARCHUNDIA, E. +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The improved dynamic slicing for spectrum-based fault localization. [PDF]
PeerJ Comput Sci, 2022 Cao H, Wang F, Deng M, Li L.
europepmc +1 more source
Analysis of fault networks and conjugate systems
, 2013 Faults networks exist over a range of scales and are important for understanding the brittle deformation and fluid transport processes within the Earth’s crust.
Nixon, Casey William
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Entropy, 2018 Aiming to solve the problem of accurate diagnosis of the size and location of rolling bearing faults, a novel quantitative and localization fault diagnosis method of the rolling bearing is proposed based on the quantitative mapping model (QMM). The fault
Jialong Wang, Lingli Cui, Yonggang Xu
doaj +1 more source
Detraque: Dynamic execution tracing techniques for automatic fault localization of hardware design code. [PDF]
PLoS One, 2022 Wu J +6 more
europepmc +1 more source