Results 81 to 90 of about 65,597 (292)

SequenceR: Sequence-to-Sequence Learning for End-to-End Program Repair

, 2019
This paper presents a novel end-to-end approach to program repair based on sequence-to-sequence learning. We devise, implement, and evaluate a system, called SequenceR, for fixing bugs based on sequence-to-sequence learning on source code.
Chen, Zimin, Kommrusch, Steve, Monperrus, Martin, Poshyvanyk, Denys, Pouchet, Louis-Noël, Tufano, Michele   +5 more
core   +1 more source

Fault Localization in Constraint Programs [PDF]

2010 22nd IEEE International Conference on Tools with Artificial Intelligence, 2010
Constraint programs such as those written in highlevel modeling languages (e.g., OPL [15], ZINC [14], or COMET [16]) must be thoroughly verified before being used in applications. Detecting and localizing faults is therefore of great importance to lower the cost of the development of these constraint programs.
Lazaar, Nadjib, Gotlieb, Arnaud, Lebbah, Yahia   +2 more
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Feature-Based Fault Localization in Evolving Software: Leveraging Regression Testing Insights

IEEE Access
Fault localization remains a vital yet resource-intensive task, particularly within software evolution, where swift and accurate fault localization is crucial.
Faeze Aghazade-Par, Mojtaba Vahidi-Asl
doaj   +1 more source

Learning Tractable Probabilistic Models for Fault Localization

, 2015
In recent years, several probabilistic techniques have been applied to various debugging problems. However, most existing probabilistic debugging systems use relatively simple statistical models, and fail to generalize across multiple programs.
Domingos, Pedro, Nath, Aniruddh
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Fault Localization With Weighted Test Model in Model Transformations

IEEE Access, 2020
Model transformations and model-driven engineering (MDE) have been applied widely in service-oriented architecture based information systems. To support the development of such a service-oriented information system, it is necessary to guarantee the ...
Pengfei Li, Mingyue Jiang, Zuohua Ding
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Modelling uncertainty for leak localization in Water Networks [PDF]

, 2018
The performance and success of model-based leak localization methods applied to water distribution networks (WDN) highly depends on the uncertainty of the system considered. This work proposes an original method of modeling the effect of uncertainties in
Blesa Izquierdo, Joaquim, Pérez Magrané, Ramon   +1 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source