Results 111 to 120 of about 12,124 (305)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Approximate Entropy Based Fault Localization and Fault Type Recognition for Non-solidly Earthed Network

Measurement Science Review, 2012
For non-solidly earthed network, the fault localization of single phase grounding fault has been a problem. A novel fault localization and fault type recognition method of single phase grounding fault based on approximate entropy is presented.
Pang Qingle, Liu Xinyun, Sun Bo, Ling Qunli   +3 more
doaj   +1 more source

Prioritizing Tests for Fault Localization

, 2013
Maritime Safety and Security Systems of Systems (MSS SoS) evolve dynamically during operation, i.e., at runtime. After each runtime evolution, the quality assurance of the integrated system of systems has to be verified again.
Alberto Gonzalez-Sanchez, Hans-Gerhard Gross, Éric Piel, Rui Abreu, Arjan J. C. van Gemund   +4 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Which Neural Network to Choose for Post-Fault Localization, Dynamic State Estimation, and Optimal Measurement Placement in Power Systems? [PDF]

Front Big Data, 2021
Afonin A, Chertkov M.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Research on autonomous fault location algorithm for distribution network based on high performance neural network

Diance yu yibiao
Due to the influence of various noises and interferences on the fault current signal of distribution network, the characteristics of the fault signal are complex and varied, making fault location difficult.
MAI Jiayi, HOU Zufeng, LIANG Yuan, LIU Moujun, YAO Fang   +4 more
doaj   +1 more source

Fault Localization on Verification Witnesses

AbstractWhen verifiers report an alarm, they export a violation witness (exchangeable counterexample) that helps validate the reachability of that alarm. Conventional wisdom says that this violation witness should be very precise: the ideal witness describes a single error path for the validator to check.
Dirk Beyer 0001, Matthias Kettl, Thomas Lemberger 0002   +2 more
openaire   +1 more source

Automated crash fault localization

, 2020
Debugging application crashes is an expensive and time-taking process, relying on the developer’s expertise, and requiring knowledge about the system.
Popping, Sven (author)
core  

Cross-domain network fault localization [PDF]

, 2009
Prior research has focused on intra-domain fault localization leaving the cross-domain problem largely unaddressed. Faults often have widespread effects, which if correlated, could significantly improve fault localization.
Fischer, William D.
core