Results 101 to 110 of about 42,007 (315)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

An Adaptive Simplified Travelling Wave‐Based Fault Detection, Classification and Location Estimation Strategy for Series Compensated Transmission Lines

open access: yesIET Smart Grid
Faults in power transmission systems pose significant challenges due to the complexity and length of transmission lines. Effective fault detection, classification and location are essential for preventing further damage to the power grid.
Ehsan Akbari, Milad Samady Shadlu
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

An Improved Methodology to Locate Faults in Onshore Wind Farm Collector Systems

open access: yesEnergies
This paper explores the growing integration of Inverter-Based Resources (IBRs) into power systems and their effects on fault diagnosis strategies. Notably, the technical literature lacks assessments of the impacts and proposals for solutions for phasor ...
Moisés Davi   +6 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Hosting Byzantine Fault Tolerant Services on a Chord ring

open access: yes, 2011
Submitted to DSN 2007 Workshop on Architecting Dependable SystemsIn this paper we demonstrate how stateful Byzantine Fault Tolerant services may be hosted on a Chord ring.
Dearle, Alan   +2 more
core  

Ground reaction force sensor fault detection and recovery method based on virtual force sensor for walking biped robots [PDF]

open access: yes, 2013
This paper presents a novel method for ground force sensor faults detection and faulty signal reconstruction using Virtual force Sensor (VFS) for slow walking bipeds. The design structure of the VFS consists of two steps, the total ground reaction force (
Hashlamon, Iyad   +3 more
core   +1 more source

Research on Distribution Network Fault Location Based on Electric Field Coupling Voltage Sensing and Multi-Source Information Fusion

open access: yesEnergies
As the last link of power transmission, the safe operation of the distribution network directly affects the experience of power users, and short-time distribution network faults can cause huge economic losses.
Bo Li   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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