Results 41 to 50 of about 26,383 (264)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
In order to solve the problems such as complex fault branch determination, large fault location error and low error tolerance of the existing multi-terminal transmission line (MTTL) fault location method, due to the influence of fault traveling wave (FTW)
Jupeng Zeng +6 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The fault location method based on the natural frequency of the fault travelling wave has outstanding superiority in high‐voltage dc system, because of high operation speed, acceptable sampling rate, and so on.
Chenyang Ma +7 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Accurate Fault Location Method of the Mechanical Transmission System of Shearer Ranging Arm
In the process of coal mine production, the fault of the mechanical transmission system of the shearer ranging arm directly affects safety production. Therefore, it is very important to achieve the accurate fault location of the shearer ranging arm.
Qinghua Mao +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Accurate fault location is crucial for enabling maintenance personnel to quickly reach the fault site for inspection and repair, thereby minimizing power outage duration.
Guangjie Yang +7 more
doaj +1 more source
Research on Non-contact Fault Location System of Traction Power Supply Line
The traditional fault location system of railway traction system is mostly based on the impedance calculation principle,which is greatly affected by the line parameters. The problem can be avoided by using traveling wave ranging principle.
Yantao ZHAI +4 more
doaj

