Results 61 to 70 of about 2,125,753 (243)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Accurate Fault Location Method of the Mechanical Transmission System of Shearer Ranging Arm
IEEE Access, 2020 In the process of coal mine production, the fault of the mechanical transmission system of the shearer ranging arm directly affects safety production. Therefore, it is very important to achieve the accurate fault location of the shearer ranging arm.
Qinghua Mao +5 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
EnergiesAccurate fault location is crucial for enabling maintenance personnel to quickly reach the fault site for inspection and repair, thereby minimizing power outage duration.
Guangjie Yang +7 more
doaj +1 more source
Research on Non-contact Fault Location System of Traction Power Supply Line
机车电传动, 2021 The traditional fault location system of railway traction system is mostly based on the impedance calculation principle,which is greatly affected by the line parameters. The problem can be avoided by using traveling wave ranging principle.
Yantao ZHAI +4 more
doaj
FAULT LOCATION ON A DISTRIBUTION FEEDER USING FAULT GENERATED HIGH FREQUENCY CURRENT SIGNATURES
ASEAN Journal on Science and Technology for Development, 2017 This paper describes how the fault generated travelling waves detected in the current signals at a single location on a distribution feeder can be used for fault location.
Hashim Hizam, P.A. Crossley
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Method for locating secondary circuit faults in substations based on graph neural networks
HeliyonTo improve the accuracy and portability of fault location in secondary circuits of smart substations, a fault location method for secondary circuits based on graph neural networks is proposed.
Ziping Peng +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source