Results 51 to 60 of about 2,125,753 (243)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Paleoearthquakes of the Düzce fault (North Anatolian Fault Zone): Insights for large surface faulting earthquake recurrence [PDF]
Copyright 2008 by the American Geophysical Union.The 12 November 1999 Mw 7.1 earthquake ruptured the Düzce segment of the North Anatolian Fault Zone and produced a ∼40-km-long surface rupture.
D. Pantosti +20 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Real-time fault diagnosis and fault-tolerant control [PDF]
This "Special Section on Real-Time Fault Diagnosis and Fault-Tolerant Control" of the IEEE Transactions on Industrial Electronics is motivated to provide a forum for academic and industrial communities to report recent theoretic/application results in ...
Cecati, Carlo +2 more
core +1 more source
The fault location method based on the natural frequency of the fault travelling wave has outstanding superiority in high‐voltage dc system, because of high operation speed, acceptable sampling rate, and so on.
Chenyang Ma +7 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
In order to solve the problems such as complex fault branch determination, large fault location error and low error tolerance of the existing multi-terminal transmission line (MTTL) fault location method, due to the influence of fault traveling wave (FTW)
Jupeng Zeng +6 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Utilização de medição fasorial sincronizada em metodologias de localização de faltas em linhas de transmissão [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Elétrica, Florianópolis, 2009.Neste trabalho, investiga-se a utilização de dados de sistemas de medição fasorial sincronizada em ...
Benetti, Marcelo Azevedo
core

