Results 71 to 80 of about 2,125,753 (243)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The walls boundary fault zone and the MØre TrØndelag fault complex:: a case study of two reactivated fault zones. [PDF]
, 2001 It is commonly observed that ancient faults or shear zones can become reactivated again and again, either within the same or even superimposed tectonic episodes, yet millions of years apart.
Watts, Lee Mark
core
Selection of sensors by a new methodology coupling a classification technique and entropy criteria [PDF]
, 2007 Complex industrial processes invest a lot of money in sensors and automation devices to monitor and supervise the process in order to guarantee the production quality and the plant and operators safety.
Elgue, Sébastien +7 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
To address issues such as inadequate fault tolerance, long computation time, and limited universality in fault location for active distribution networks, this paper proposes a fault location method that combines Petri nets with an improved particle swarm
Jie Yang +4 more
core +1 more source
Fault Location on Three-Terminal Transmission Lines Without Utilizing Line Parameters
ElectricityTransmission lines are constantly exposed to changes in climatic conditions and aging which affect the parameters and change the characteristics of the three-terminal circuit over time.
Hongchun Shu +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2015 This paper presents a neural network method to locate common fault exactly in a distribution power system (DPS) with renewable sources. The back propagation (BP) neural network method is applied to identify patterns of voltage and current measured from ...
Li XH(李先宏) +10 more
core +1 more source
Application of multiple resistive superconducting fault-current limiters for fast fault detection in highly interconnected distribution systems [PDF]
, 2013 Superconducting fault-current limiters (SFCLs) offer several benefits for electrical distribution systems, especially with increasing distributed generation and the requirements for better network reliability and efficiency.
Burt, Graeme +3 more
core +3 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source