Results 61 to 70 of about 18,199 (263)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
There are many potential fault risks in distribution automation system. If the fault is not diagnosed in time, the power supply quality will be affected.
WU Longteng, HE Jianjun, GUO Qian
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Research of fault diagnosis and prediction for diesel engine based on probabilistic neural network
In view of problem of difficult fault diagnosis and prediction for diesel engine, the paper analyzed common faults and influencing factors of diesel engine, introduced method of extraction, analysis and processing of the failure data, and built a model ...
ZHENG Xiao-qian, HU Shi-qiang, WU Jian
doaj +1 more source
Estimating System State through Similarity Analysis of Signal Patterns
State prediction is not straightforward, particularly for complex systems that cannot provide sufficient amounts of training data. In particular, it is usually difficult to analyze some signal patterns for state prediction if they were observed in both ...
Kichang Namgung +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Collaborative Fusion Attention Mechanism for Vehicle Fault Prediction
In this study, we investigate a deep learning-based vehicle fault prediction model aimed at achieving accurate prediction of vehicle faults by analyzing the correlations among different faults and the impact of critical faults on future fault development.
Hong Jia +3 more
doaj +1 more source

