Results 81 to 90 of about 17,917 (263)

Remaining Useful Life Prediction and Fault Diagnosis of Rolling Bearings Based on Short-Time Fourier Transform and Convolutional Neural Network

Shock and Vibration, 2020
Rolling bearings play a pivotal role in rotating machinery. The remaining useful life prediction and fault diagnosis of bearings are crucial to condition-based maintenance.
Shuang Zhou, Maohua Xiao, Petr Bartos, Martin Filip, Guosheng Geng   +4 more
doaj   +1 more source

Estimating System State through Similarity Analysis of Signal Patterns

Sensors, 2020
State prediction is not straightforward, particularly for complex systems that cannot provide sufficient amounts of training data. In particular, it is usually difficult to analyze some signal patterns for state prediction if they were observed in both ...
Kichang Namgung, Hyunsik Yoon, Sujeong Baek, Duck Young Kim   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Collaborative Fusion Attention Mechanism for Vehicle Fault Prediction

Future Internet
In this study, we investigate a deep learning-based vehicle fault prediction model aimed at achieving accurate prediction of vehicle faults by analyzing the correlations among different faults and the impact of critical faults on future fault development.
Hong Jia, Dalin Qian, Fanghua Chen, Wei Zhou   +3 more
doaj   +1 more source

Prediction Model of Vibration Feature for Equipment Maintenance Based on Full Vector Spectrum

Shock and Vibration, 2017
Establishing a prediction model is a key step for the implementation of prognostic and health management. The prediction model can be used to forecast the change trend of the characteristics of the vibration signal and analyze the potential failure in ...
Lei Chen, Jie Han, Wenping Lei, ZhenHong Guan, Yajuan Gao   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Research on fault time prediction method for high speed rail BTM unit based on multi method interactive validation

High-Speed Railway
The Balise Transmission Module (BTM) unit of the on-board train control system is a crucial component. Due to its unique installation position and complex environment, this unit has a higher fault rate within the on-board train control system. To conduct
Limin Fu, Junqiang Gou, Chao Sun, Hanrui Li, Wei Liu   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source