Results 61 to 70 of about 445,363 (308)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Service restoration strategy for active distribution networks considering source-load uncertainty

International Journal of Electrical Power & Energy Systems
Active distribution networks (ADNs) incorporate numerous distributed generations (DGs) and energy storage systems. When sudden faults occur in the system, service restoration can be enhanced through microgrid formation and network reconfiguration ...
Hongchun Shu, Hongfang Zhao, Xuezhuan Zhao   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Defense strategy against cyber-physical coordinated false data injection attacks in cyber-physical power systems

Results in Engineering
With the deep integration of cyber-physical power systems (CPPS), cyber-physical coordinated false data injection attacks (FDIAs) have emerged as a new risk threatening the security of power grids.
Hongchun Shu, Hongfang Zhao, Yongyin Yang, Yutao Tang   +3 more
doaj   +1 more source

Measurement-free topological protection using dissipative feedback [PDF]

, 2014
Protecting quantum information from decoherence due to environmental noise is vital for fault-tolerant quantum computation. To this end, standard quantum error correction employs parallel projective measurements of individual particles, which makes the ...
Fujii, Keisuke, Imoto, Nobuyuki, Kitagawa, Masahiro, Negoro, Makoto   +3 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Advanced control strategy for wind-storage to compensate hammer effect based on SID and FRR

International Journal of Electrical Power & Energy Systems
To address the seasonal variations in frequency regulation requirements (FRRs) for a hybrid renewable hydropower system, this study proposes an advanced wind-storage coordinated control strategy to compensate for the water hammer effect, based on system ...
Hongchun Shu, Jing Chen, Botao Shi, Guangxue Wang, Xi Wang, Shunguang Lei   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Research on the improved hybrid DC circuit breaker with voltage-limiting and current-limiting capability

International Journal of Electrical Power & Energy Systems
The DC circuit breaker (DCCB) is a critical device that ensures the safe and reliable operation of the DC transmission system. As the level of DC voltage and transmission power increases, the flexible DC grid will need more and more opening capacity of ...
Hongchun Shu, Zongxue Shao, Yue Dai
doaj   +1 more source

Improved protection system for phase faults on marine vessels based on ratio between negative-sequence and positive-sequence of the fault current [PDF]

, 2018
This paper presents a new method to protect the radial feeders on marine vessels. The proposed protection method is effective against Phase-Phase (PP) faults and is based on evaluation of the ratio between the negative-sequence and positive-sequence of ...
Bak, Claus, Blaabjerg, Frede, Booth, Campbell, Ciontea, Catalin, Hong, Qiteng, Madsen, Kjeld, Sterregaard, Claes   +6 more
core   +2 more sources