Results 81 to 90 of about 612,817 (305)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Observer-based Fault Detection and Diagnosis for Mechanical Transmission Systems with Sensorless Variable Speed Drives [PDF]

open access: yes, 2015
Observer based approaches are commonly embedded in sensorless variable speed drives for the purpose of speed control. It estimates system variables to produce errors or residual signals in conjunction with corresponding measurements. The residual signals
Abusaad, Samieh   +3 more
core  

Slip inversion along inner fore-arc faults, eastern Tohoku, Japan [PDF]

open access: yes, 2017
The kinematics of deformation in the overriding plate of convergent margins may vary across timescales ranging from a single seismic cycle to many millions of years.
Fisher, Donald M.   +4 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The results of geothermal and geoelectric studies in the regions of Rivne, Khmelnitsky and Uzhno Ukrainsk NPPs

open access: yesГеофизический журнал, 2020
The main task of the work was to present for the first time the results of geothermal and geoelectric studies obtained in the tectonosphere department and comparing them with other geological and geophysical data. Unfortunately, geothermal data near all
I.M. Logvinov   +2 more
doaj   +1 more source

Fault Detection and Diagnosis in Air Conditioners and Refrigerators [PDF]

open access: yes, 1999
A fault detection and diagnosis (FDD) method was used to detect and diagnose faults on both a refrigerator and an air conditioner during normal cycling operation.
Bullard, C.W.   +2 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Fault Information Processing of Power Dispatching Communication System Combining MMSE Algorithm and LMS

open access: yesIEEE Access
As the scale of power dispatching communication system expands day by day, it becomes more and more difficult for operators to deal with fault information.
Lianrong Pan   +4 more
doaj   +1 more source

Arcing High Impedance Fault Detection Using Real Coded Genetic Algorithm

open access: yes, 2007
Safety and reliability are two of the most important aspects of electric power supply systems. Sensitivity and robustness to detect and isolate faults can influence the safety and reliability of such systems.
Al-Othman, A.K.   +2 more
core  

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