Results 171 to 180 of about 856,908 (346)

POCKET BOOK AS AN EDUCATIONAL METHOD TO IMPROVE PATIENT’S KNOWLEDGE AND ADHERENCE TO RATIONAL ANTIBIOTIC USE: A RANDOMIZED CONTROLLED TRIAL IN SURABAYA [PDF]

open access: yes, 2012
Background: Irrational use of antibiotics has caused bacterial resistances. The lack of understanding of antibiotic use contributes to this phenomenon.
Hadi, Usman   +3 more
core  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Search for medicinal plants with pharmaceutical use by integration of the physical and biotic informations in a geographic information system: The interface steppe region - Saharan region (Algeria) [PDF]

open access: yes, 2015
Algeria is a large, rich country in flora and fauna. The objective of this study was the integration of biological and physical data in a GIS for research of medicinal plants.Postprint (published ...
Bousmaha, A.M.   +8 more
core   +1 more source

On the fauna of Nowaja-Semlja

open access: yesAnnals and Magazine of Natural History, 1873
(1873). On the fauna of Nowaja-Semlja. Annals and Magazine of Natural History: Vol. 11, No. 66, pp. 464-465.
openaire   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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