Results 131 to 140 of about 2,100,160 (252)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

UNC13B variants associated with partial epilepsy with favourable outcome. [PDF]

Brain, 2021
Wang J, Qiao JD, Liu XR, Liu DT, Chen YH, Wu Y, Sun Y, Yu J, Ren RN, Mei Z, Liu YX, Shi YW, Jiang M, Lin SM, He N, Li B, Bian WJ, Li BM, Yi YH, Su T, Liu HK, Gu WY, Liao WP.   +22 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Reconstrução da mama: seis anos de experiência do núcleo de cirurgia plástica do Hopital Universitário Prof. Polydoro Ernani de São Thiago - UFSC [PDF]

, 2005
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Ribeiro, Raidel Deucher.
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¹⁸F-FDG-PET hypometabolism as a predictor of favourable outcome in epilepsy surgery: protocol for a systematic review and meta-analysis. [PDF]

BMJ Open, 2022
Courtney MR, Antonic-Baker A, Sinclair B, Nicolo JP, Neal A, Law M, Kwan P, O'Brien TJ, Vivash L.   +8 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Logistic regression analysis to understand the association between the explanatory variables and the binary outcome variable–“having favourable attitude towards rabies control and prevention program or not”.

, 2019
Logistic regression analysis to understand the association between the explanatory variables and the binary outcome variable–“having favourable attitude towards rabies control and prevention program or not”.
Frank van der Meer (216287), Tenzin Tenzin (740002), Sangay Rinchen (6533003), David Hall (152584), Basant Sharma (6533006), Susan Cork (6067193), Kinzang Dukpa (6533009)   +6 more
core   +1 more source

Paediatric-type diffuse low-grade gliomas: a clinically and biologically distinct group of tumours with a favourable outcome. [PDF]

Pathologica, 2022
Fabbri VP, Caporalini C, Asioli S, Buccoliero A.   +3 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Influence of Short Birth Spacing on Pregnancy Outcome

, 2003
This descriptive study was carried out to determine the effect of short birth interval (4years, while short birth interval (
Hamid, Fatima
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