Results 151 to 160 of about 60,037 (282)

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11143-11177, December 2026.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding, Qing Liu, Qiong Luo, Xiaojun Yao, Xingxing Fan   +4 more
wiley   +1 more source

Curcumin Intervention in Diabetic Neuropathy: Molecular Mechanisms and Preclinical Insights

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review highlights curcumin's neuroprotective potential, showing how it mitigates oxidative stress and inflammation by modulating Nrf2, MAPK, and NF‐κB signaling. Preclinical data shows it stabilizes glucose metabolism and reduces nerve degradation.
Sanket Sharma, Rosaline Mishra, Rashmi Singh, Radha Goel, Praveen Kumar Gaur, Kanak Lata   +5 more
wiley   +1 more source

Spectral Response of an Embedded Fiber Bragg Grating to an Arbitrary Non-Axial Mechanical Impact. [PDF]

Sensors (Basel)
Arseniev D, Kiesewetter D, Krivosheev S, Magazinov S, Malyugin V, Kuznetsov I, Varzhel S, Dmitriev AA, Klishina V, Danilov A, Magomedova A, Sverdlik L, Han X, Sun C.   +13 more
europepmc   +1 more source

Prognostic Implications of High HFpEF Probability in Patients With Chronic Thromboembolic Pulmonary Hypertension

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Assessment of HFpEF probability using the HFpEF‐ABA algorithm identifies patients with chronic thromboembolic pulmonary hypertension at higher risk of clinical worsening. Adding HFpEF probability to COMPERA 2.0 improves prognostic discrimination and supports refined risk stratification. ABSTRACT Background Chronic thromboembolic pulmonary hypertension (
Yijia Wang, Xin Li, Zhihua Huang, Anqi Duan, Qi Wang, Luyang Gao, Sicong Li, Qing Zhao, Tao Yang, Zhihui Zhao, Qin Luo, Zhihong Liu   +11 more
wiley   +1 more source

Associations of fasting blood glucose and the triglyceride-glucose index with aggressive pathological features of papillary thyroid carcinoma. [PDF]

Front Endocrinol (Lausanne)
Xu X, Gong K, Li C, Hu Y, Liu C, Guo P, Zhao W, Wang Y, Dong B.   +8 more
europepmc   +1 more source

Realization of Optimal FBG Band–Pass Filters for High Speed HDWDM

Optical wavelength division multiplexing (WDM) communication systems are forging ahead towards higher data transmission rate and lower channel spacing to utilize available bandwidth more effectively [1].
Ozoliņš, Oskars, Ivanovs, Ģirts
core  

Experiment on Qinghai-Tibet railroad subgrade temperature monitoring based on FBG sensors

, 2005
Qinghai-Tibet Railway is the longest and highest plateau railway in the world. A long term monitoring system of the stability of the subgrade in the permafrost regions should be put forward immediately to prevent damage to the railway.
Sun, BC (Sun, Baochen), Zhang, WT (Zhang, Wentao), Liu, YL (Liu, Yuliang), Du, YL (Du, Yanliang), Zhang, WT, Chinese Acad Sci, Inst Semicond, Beijing 10083, Peoples R China.   +4 more
core  

Inflammatory and Insulin Resistance Indicator for Predicting Repeat Revascularization and In‐Stent Restenosis in Patients With Chronic Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Clinical Cardiology, Volume 49, Issue 11, November 2026.
In patients with chronic coronary syndrome undergoing PCI, higher baseline CTI was independently associated with repeat revascularization and in‐stent restenosis. However, its incremental predictive value beyond conventional risk factors was limited, highlighting the need for further validation.
Wang Jiale, Liu Longcheng, Lu Peipei, Ma Lihong   +3 more
wiley   +1 more source

Association of ALI and mCONUT With In‐Hospital De Novo Heart Failure in Patients With STEMI

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Among 1598 patients with first‐time STEMI, both the advanced lung cancer inflammation index (ALI) and the modified Controlling Nutritional Status (mCONUT) score independently predicted in‐hospital de novo heart failure. mCONUT outperformed ALI (AUC 0.706 vs.
Zhiyin Dai, Lijuan Yang, Rui Chen, Ye Zhou, Wei Yuan, Duzhe Jiang, Junjie Liu   +6 more
wiley   +1 more source

Highly Sensitive Strain Sensing Using a Resonant Fiber Bragg Grating. [PDF]

Micromachines (Basel)
Ashkenazy E, Krylov S, Tur M.
europepmc   +1 more source