Results 91 to 100 of about 14,752 (202)

Analysis of a compartmental model of endogenous immunoglobulin G metabolism with application to multiple myeloma [PDF]

, 2017
Immunoglobulin G (IgG) metabolism has received much attention in the literature for two reasons: (i) IgG homeostasis is regulated by the neonatal Fc receptor (FcRn), by a pH-dependent and saturable recycling process, which presents an interesting ...
Arnulf, Bertrand, Avet-Loiseau, Hervé, Chappell, Michael J., Decaux, Olivier, Dejoie, Thomas, Evans, Neil D., Fouquet, Guillemette, Guidez, Stéphanie, Harding, Stephen, Harel, Stéphanie, Hebraud, Benjamin, Javaugue, Vincent, Kendrick, Felicity, Leleu, Xavier, Moreau, Philippe, Richez, Valentine, Schraen, Susanna, Touzeau, Cyrille   +17 more
core   +2 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo.

PLoS ONE, 2019
Proteinuria is strongly associated with kidney disease progression but the mechanisms underlying podocyte handling of serum proteins such as albumin and IgG remain to be elucidated.
James Dylewski, Evgenia Dobrinskikh, Linda Lewis, Pantipa Tonsawan, Makoto Miyazaki, Parmjit S Jat, Judith Blaine   +6 more
doaj   +1 more source

AEC in A Netshell: on Target and Topology Choices for FCRN Acoustic Echo Cancellation [PDF]

, 2021
Jan Franzen, Ernst Seidel, Tim Fingscheidt   +2 more
openalex   +1 more source

An intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin G [PDF]

, 2010
Recent advances in imaging techniques along with more powerful in vitro and in vivo models of receptor-mediated ligand transport are facilitating advances in our understanding of how cells efficiently direct receptors and their cargo to target ...
Bjorkman, Pamela J., Tesar, Devin B.
core   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source

Localization of neonatal Fc receptor for IgG in aggregated lymphoid nodules area in abomasum of Bactrian camels (Camelus bactrianus) of different ages

BMC Veterinary Research, 2016
Background The neonatal Fc receptor (FcRn) plays a crucial role in transporting IgG and associated antigens across polarized epithelial barriers in mucosal immunity. However, it was not clear that FcRn expression in aggregated lymphoid nodules area (ALNA)
Wang-Dong Zhang, Wen-Hui Wang, Shu-Xian Li, Shuai Jia, Xue-Feng Zhang, Ting-Ting Cao   +5 more
doaj   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

The neonatal Fc receptor (FcRn) is a pan-arterivirus receptor

Nature Communications
Arteriviruses infect a variety of mammalian hosts, but the receptors used by these viruses to enter cells are poorly understood. We identified the neonatal Fc receptor (FcRn) as an important pro-viral host factor via comparative genome-wide CRISPR ...
Teressa M. Shaw, Devra Huey, Makky Mousa-Makky, Jared Compaleo, Kylie Nennig, Aadit P. Shah, Fei Jiang, Xueer Qiu, Devon Klipsic, Raymond R. R. Rowland, Igor I. Slukvin, Meagan E. Sullender, Megan T. Baldridge, Haichang Li, Cody J. Warren, Adam L. Bailey   +15 more
doaj   +1 more source

Warm Autoimmune Haemolytic Anaemia Management in Asia‐Pacific: A Delphi Panel Expert Consensus and Systematic Literature Review

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Objective This study aimed to assess the burden of warm autoimmune haemolytic anaemia (wAIHA) and treatment practices in the Asia‐Pacific (APAC) region. Methods A systematic literature review (SLR) of observational studies in adult patients with wAIHA was conducted.
Phil Choi, Alberta Hoi, Rong Fu, Jun‐ho Jang, Yok Lam Kwong, Yoshitaka Miyakawa, Chi‐Chiu Mok, Hiroaki Niiro, Yasutaka Ueda, Robert Bagnall, Petya Kodjamanova, Da Eun Ahn, Nakul Saxena, Bryan Wahking, Shin‐Seok Lee   +14 more
wiley   +1 more source