Results 111 to 120 of about 18,936 (261)
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
The Distortionary Effects of Government Procurement: Evidence from Medicaid Prescription Drug Purchasing [PDF]
The federal-state Medicaid program insures 43 million people for virtually all of the prescription drugs approved by the FDA. To determine the price that it will pay for a drug treatment, the government uses the average price in the private sector for ...
Mark Duggan, Fiona Scott Morton
core
Schematic diagram of primary screening of 1600 FDA approved drugs.
, 2013 Schematic diagram of primary screening of 1600 FDA approved drugs.
Giulio M. Pasinetti (419134) +12 more
core +1 more source
Properties of FDA-approved small molecule protein kinase inhibitors: A 2025 update
Pharmacological ResearchBecause of the deregulation of protein kinase action in many inflammatory diseases and cancer, the protein kinase family has become one of the most significant drug targets in the 21st century.
Robert Roskoski, Jr.
doaj +1 more source
Advanced Materials, EarlyView.A new benign solvent (1,3‐diphenylacetone) enables a simple, safe, and sustainable dissolution and gelation method to convert waste PET into low density, monolithic aerogels with high mechanical strength (E = 20 MPa) and remarkably low thermal conductivity (k = 21.9 to 28.9 mW/m·K).
Kira R. Baugh +9 more
wiley +1 more source
Scientific ReportsU.S. laws enacted since 1983 have aimed to enhance the development and marketing of new pharmaceutical products. We thoroughly characterized all new molecular entities, therapeutic biologics, and gene and cell therapies approved by the US Food and Drug ...
Enrique Seoane-Vazquez +2 more
doaj +1 more source
A Pressure Microsensor Made of Parylene‐C for Use as Medical Implant
Advanced Materials Technologies, EarlyView.A monolithic parylene‐C pressure sensor with gold strain gauges provides 6.2 μV$\mu{\rm V}$·mmHg$\cdot{\rm mmHg}$−1$^{-1}$ sensitivity. The morphology of a sputtered thin film strain sensor is granular/columnar, which results in a high gauge factor of 7.5. Thermal bonding and parylene‐C coating create a hermetic cavity.
Ann‐Kathrin Klein +2 more
wiley +1 more source
Advanced Robotics Research, EarlyView.Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin +3 more
wiley +1 more source