Results 31 to 40 of about 4,829,888 (359)
Valuation implications of pharmaceutical companies' R&D regulatory approval notifications [PDF]
, 2013 This paper examines shareholder wealth effects surrounding applications to, and approvals by, the United States Food and Drug Administration (FDA) for firms listed on the New York (NYSE) and London (LSE) stock exchanges.
Hamill, P.A., McIlkenny, P., Opong, K.K.
core +1 more source
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Antimicrobial Agents and Chemotherapy, 2020 Drug repositioning is the only feasible option to immediately address the COVID-19 global challenge. We screened a panel of 48 FDA-approved drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which were preselected by an assay of ...
Sangeun Jeon +7 more
semanticscholar +1 more source
New Medical Device and Therapeutic Approvals in Otolaryngology: State of the Art Review of 2021
OTO Open, 2022 Objective To evaluate new medical devices and drugs pertinent to otolaryngology–head and neck surgery that were approved by the Food and Drug Administration (FDA) in 2021. Data Sources Publicly available FDA device and drug approvals from ENT (ear, nose,
Alexander M. Choi MD +18 more
doaj +1 more source
The FDA “black box” warning on antidepressant suicide risk in young adults: More harm than benefits? [PDF]
, 2019 The decision made in the year 2004 by the U.S. Food and Drug Administration (FDA) to require a boxed warning on antidepressants regarding the risk of suicidality in young adults still represents a matter of controversy.
Anastasia A. +12 more
core +1 more source
Scientific Reports, 2023 Patients endure risk and uncertainty when they participate in clinical trials. We previously estimated that 12,217 patient-participants are required to bring a new cancer drug to market.
Charlotte Ouimet +5 more
doaj +1 more source
The Lancet Regional Health. Americas, 2023 Summary: Background: Most cancer drugs enter the US market first. US Food and Drug Administration (FDA) approvals of new cancer drugs may influence regulatory decisions in other settings.
Adriana M. Ivama-Brummell +7 more
doaj +1 more source
Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]
, 2014 A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core +3 more sources
Alchemical analysis of FDA approved drugs
Digital Discovery, 2023 Reaction informatics is used to map the chemical space of drugs paired by similarity according to different molecular fingerprints.
Markus Orsi +3 more
openaire +3 more sources
Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease
Life Science, 2020 Aims In December 2019, the Coronavirus disease-2019 (COVID-19) virus has emerged in Wuhan, China. In this research, the first resolved COVID-19 crystal structure (main protease) was targeted in a virtual screening study by of FDA approved drugs dataset ...
Mahmoud Kandeel, M. Al-Nazawi
semanticscholar +1 more source
, 2008 The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008.
Ravi Iyengar
core +2 more sources