Results 51 to 60 of about 453,200 (223)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Lérida de la Caridad de la Torre Castillo (Pucha): mujer de ciencia y fe
Gaceta Médica Estudiantil, 2020 Lérida de la Caridad de la Torre Castillo, Pucha, nació el 10 de diciembre de 1950 en la provincia Guantánamo. Comenzó su vida laboral como maestra en la Escuela Primaria “Manuel Ascunce Domenech”.
Zayda de la Luz Reyes-García +1 more
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FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Teología el pecado original en Paciano de Barcelona
Estudios Eclesiásticos, 1990 Este artículo analiza la aportación de San Paciano en su obra "De Baptismo" a los adultos que iban a recibir el bautismo en su diócesis de Barcelona. Paciano trataba de introducir a sus feligreses en las verdades del Misterio. Su explicación partía de la
Carmelo Granado Bellido
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Fides – I: cultivar la dimensión transcendente
Revista de Fomento Social, 2008 En este estudio se aborda el reto de proponer una presencia viva y firme de la fides en las universidades jesuitas que, por un lado, respete en todo momento e incluso incentive lo que la universidad es y, por otro lado, acoja, a la vez lúcida y ...
Xabier Etxeberria Mauleón
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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Yankuang ceshi, 2014 The traditional solid phase extraction sorbent contains certain deficiencies in the progress of processing heavy metals in environmental samples, such as pH instability and co-extraction difficulty.
SUN Na +3 more
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