Results 61 to 70 of about 471,302 (247)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Determination of Lead, Cadmium, Copper and Iron Contents in Water by Multi-walled Carbon Nanotubes-solid Phase Extraction

open access: yesYankuang ceshi, 2014
The traditional solid phase extraction sorbent contains certain deficiencies in the progress of processing heavy metals in environmental samples, such as pH instability and co-extraction difficulty.
SUN Na   +3 more
doaj  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Fundamentos teológicos de la nueva evangelización

open access: yesEstudios Eclesiásticos, 2017
Esta conferencia responde a la pregunta, qué significa nueva evangelización. Para ello, el autor señala el fundamento bíblico de este concepto, explica su contenido a la luz de Heb 13,8 y desarrolla una reflexión sobre su método (cf.
Rino Fisichella
doaj  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

AS CORES DO SOLO COMO PARÂMETRO PARA DELIMITAÇÃO DO AMBIENTE DE UMA VEREDA

open access: yesBoletim Goiano de Geografia, 2019
As veredas estão dispostas na paisagem em áreas rebaixadas e alagadiças, que contribuem para regular o ciclo hidrológico de abastecimento dos cursos d’água.
Glauber Stefan Barbosa   +2 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Pasado y presente de la Teología de la Liberación en América Latina

open access: yesPolítica Internacional
La existencia de la Teología de la Liberación por más de una década en América Latina constituyó un periodo de concientización de las masas a través de un pensamiento religioso- político que ahondó en las raíces del cristianismo junto a la reivindicación
Belkiss Elena Comas Martínez   +1 more
doaj   +1 more source

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