Results 61 to 70 of about 4,634,794 (327)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Sulphur and zinc abundances in Galactic stars and damped Lyman-alpha systems

, 2003
High resolution spectra of 34 halo population dwarf and subgiant stars have been obtained with VLT/UVES and used to derive sulphur abundances from the 8694.0, 8694.6 A and 9212.9, 9237.5 A SI lines.
Alonso, Alonso, Alonso, Asplund, Asplund, Asplund, Asplund, Biémont, Boissier, Calura, Carigi, Carney, Carpenter, Carretta, Centurión, Centurión, Chen, Chiappini, Dekker, Dekker, Dessauges-Zavadsky, Ellison, Feltzing, François, François, Fuhrmann, Goswami, Gratton, Gratton, Grevesse, Hill, Holweger, Israelian, Jenkins, Kanekar, Kirkman, Kiselman, Kiselman, Lambert, Ledoux, Lopez, Lopez, Lu, M. Asplund, M. Pettini, Matteucci, Mishenina, Mitchell, Mo, Molaro, Nakamura, Nissen, Nissen, Nissen, Norris, P. E. Nissen, Petitjean, Pettini, Pettini, Pettini, Prochaska, Prochaska, Prochaska, Ryan, Ryde, Savage, Schuster, Schuster, Seaton, Shchukina, Shetrone, Sneden, Stephens, Takada-Hidai, Thévenin, Tolstoy, Uitenbroek, VandenBerg, Vladilo, Vladilo, Y. Q. Chen   +80 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Es cuestión del corazón

Revista Eídos, 2009
El artículo aborda un tema relacionado con la necesidad de una vida espiritual del ser humano, que le permita desenvolverse en el mundo empresarial con solvencia, junto a la formación académica, a sus competencias profesionales y a la experiencia en el ...
Mercedes Sarrade Peláez
doaj   +1 more source

Redox and Spectroscopic Properties of Iron Porphyrin Nitroxyl in the Presence of Weak Acids [PDF]

, 2017
The spectroelectrochemistry and voltammetry of Fe(OEP) (NO) in the presence of substituted phenols was studied. Cyclic voltammetry showed that two closely spaced waves were observed for the reduction of Fe(OEP) (NO) in the presence of substituted phenols.
Rahman, Md. Hafizur, Ryan, Michael D.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Intrinsic and structural isotope effects in Fe-based superconductors [PDF]

, 2010
The currently available results of the isotope effect on the superconducting transition temperature T_c in Fe-based high-temperature superconductors (HTS) are highly controversial.
A. Bussmann-Holder, C. P. Poole, H. Keller, J. P. Franck, M. Bendele, R. Khasanov   +5 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source