Results 51 to 60 of about 4,634,794 (327)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Study on Color-causing Elements in Qinghai Nephrite by Elemental Analysis and Electron Paramagnetic Resonance Spectroscopy

Yankuang ceshi, 2019
BACKGROUND Color is the important manifestation of nephrite value. Qinghai nephrite has different colors, but there is a lack of research on coloration. In recent years, the study on the coloration of nephrite in Qinghai mainly focused on azure-green and
YU Hai-yan, RUAN Qing-feng, SHA Xin, YANG Yu-fu   +3 more
doaj   +1 more source

Calculated oscillation periods of the interlayer coupling in Fe/Cr/Fe and Fe/Mo/Fe sandwiches [PDF]

Physical Review B, 1996
We have performed an ab initio study of the oscillation periods of the interlayer coupling in sandwiches of [100] layers of body centered cubic Cr, respectively, Mo, with up to 20 monolayers thickness embedded in an Fe host. Our derived values for the oscillation periods of the interlayer coupling agree well with those expected from the respective ...
Mirbt, S., Niklasson, A.M.N., Johansson, B., Skriver, Hans Lomholt   +3 more
openaire   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Purification of LiF Powder by Zone Melting Method [PDF]

مجله علوم و فنون هسته‌ای, 2017
In order to achieve high quality crystals, it is necessary to purify the raw material. In the present experimental study, the zone melting method was used to purify Lithium Flouride powder. A small amount of melt moves slowly from the solid area in order
R Khatiri, H Faripour, H Kalbasi, M Esmaeilnia, Z Dorriz, B Arhami, N.A Akbari, E Jangjoo   +7 more
doaj  

Kierkegaard y el salto de fe. Un acto de individualidad

HYBRIS: Revista de Filosofía, 2020
El presente ensayo tiene por objeto analizar de forma sucinta el concepto de fe a través la muy penetrante mirada del filósofo danés Sören Kierkegaard. La Fe es analizada por Kierkegaard a partir del absurdo, la resignación y la paradoja de la fe.
Jonás E. Aponte A.
doaj   +1 more source

COMMON REED (PHRAGMITES AUSTRALIS (CAV.) TRIN. EX STEUD.) AS BIOACCUMULATOR OF FE, MN, CU ON BIO-ENGINEERING FACILITIES OF POLTAVSKY MINING AND PROCESSING PLANT

Геохімія техногенезу, 2022
The goal of this study was evaluation of the total phytomass of reed per unit of square on each bio-engineering facilities (BIF), its distribution between aboveground and underground parts, biological uptake of some heavy metals (Fe, Mn, Cu) by the total
O.O. Orlov , V.V. Dolin , D.V. Charny , D.O. Yarochshuk   +3 more
doaj   +1 more source

Isotope shifts and hyperfine structure of the Fe I 372 nm resonance line

, 2009
We report measurements of the isotope shifts of the $3d^64s^2 a ^5D_4 - 3d^64s4p z ^5F_5^o$ Fe I resonance line at 372 nm between all four stable isotopes $^{54}$Fe, $^{56}$Fe, $^{57}$Fe, and $^{58}$Fe, as well as the complete hyperfine structure of that
H. M. Crosswhite, I. I. Sobel’man, J. von Zanthier, J. Z. Klose, N. Huet, S. Krins, S. Oppel, T. Bastin, W. H. King   +8 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Bias voltage effects on tunneling magnetoresistance in Fe/MgAl${}_2$O${}_4$/Fe(001) junctions: Comparative study with Fe/MgO/Fe(001) junctions [PDF]

, 2017
We investigate bias voltage effects on the spin-dependent transport properties of Fe/MgAl${}_2$O${}_4$/Fe(001) magnetic tunneling junctions (MTJs) by comparing them with those of Fe/MgO/Fe(001) MTJs. By means of the nonequilibrium Green's function method
Masuda, Keisuke, Miura, Yoshio
core   +3 more sources