Results 41 to 50 of about 1,328,307 (278)

En torno a la experiencia religiosa. Ecos de la lectura de La filosofía y la experiencia religiosa de Jorge Saltor

open access: yesStudium: Filosofía y Teología, 2016
La lectura del libro de Saltor ha despertado en mí dudas e inquietudes en torno a la experiencia religiosa y a su estudio por parte de la filosofía y de la teología. No se trata de un comentario crítico al libro.
José Canal-Feijóo
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

El concepto de espera en Dos discursos edificantes de 1843

open access: yesTópicos, 2013
According to Kierkegaard in Two Edifying Discourses, faith is the waiting for something more. This waiting has to do with the future and the opening of possibilities and it avoids despair.
Leticia Valadez
doaj   +1 more source

Analisa Energi Dan Jari-jari Inti dari Fungsi Gelombang Inti Besi (Fe) Dengan Metode Skyme-Hartee-Fock

open access: yesWahana Fisika: Jurnal Penelitian Fisika dan Terapannya, 2022
Penelitian ini merupakan penelitian yang berdasarkan studi literatur dan eksperimen dengan menggunakan Metoda Skyrme-Hartree-Fock. Pada artikel ini dilakukan perhitungan nuclear ground state properties dari Fe dengan menggunakan metode Skyrme-Hartree ...
Lasmita Sari   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Dimensión sacramental y celebración canónica del matrimonio: requisitos para el acceso a las nupcias

open access: yesEstudios Eclesiásticos, 2016
La actual realidad social —con el aumento de los bautizados sin fe, de personas religiosamente indiferentes y de situaciones matrimoniales irregulares— suscita una especial preocupación pastoral por cuidar la preparación y formación para el matrimonio y ...
Carmen Peña García
doaj  

¿Cómo puede un pagano vencer al mundo? Observaciones sobre los Tres discursos edificantes de 1843

open access: yesTópicos, 2013
The 1843 Edifying Discourses seek for the escence of man and action, and they are addressed to the perfect man, not to the aesthete nor the ethical man.
Teresa Aizpún
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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