Comparison of two chemical models to induce hepatic preneoplasia in male Wistar rats
Background. One established model to induce hepatic preneoplasia (HP) (DEN 150) uses diethylnitrosamine (DEN) as initiator agent and 2-acetylaminofluorene (2-AAF) as a promoter drug. In addition, both chemicals cause liver cholestasis and fibrosis.
Marina C. Vera +5 more
doaj +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
Background Approximately 5 to 10% of all cancers are caused by inherited germline mutations, many of which are associated with different Hereditary Cancer Syndromes (HCS).
Marta Ramírez-Calvo +16 more
doaj +1 more source
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Finite element stress analysis and topological optimization of a commercial aircraft seat structure
In recent years, the Finite Element Method (FEM) has emerged as a cornerstone in the field of seating design, particularly within the aircraft industry.
Sireetorn Kuharat +5 more
doaj +1 more source
Development and Finite Element (FE) analysis of a novel short hip stem concept. [PDF]
Jahnke A +4 more
europepmc +1 more source
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Stress Concentration Factors of Concrete-Filled T-Joints under In-Plane Bending: Experiments, FE Analysis and Formulae. [PDF]
Matti F, Mashiri F.
europepmc +1 more source
Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park +7 more
wiley +1 more source
Development of Tube Hydroforming for a Tail Pipe Using FE Analysis [PDF]
S.S. Han
openalex +1 more source

