Results 31 to 40 of about 480,216 (163)

Influence of individual differences in Behavioral Inhibition System on the magnitude and time course of the fear-potentiated startle

, 2006
Previous research has shown that the startle reflex is potentiated during experimentally induced anxiety (fear-potentiated startle). In the present study, the magnitude and time course of the startle blink reflex were examined among 35 undergraduates ...
Riba, Jordi, Torrubia, Rafael, Caseras, Xavier, Barbanoj, Manel, Fullana, Miquel-Angel   +4 more
core   +1 more source

Evidence of Contextual Fear after Lesions of the Hippocampus: A Disruption of Freezing But Not Fear-Potentiated Startle

, 1997
The roles of the dorsal hippocampus and the central nucleus of the amygdala in the expression of contextual fear were assessed using two measures of conditioned fear: freezing and fear-potentiated startle.
Michael Davis, Jonathan C. Gewirtz, Kenneth A. McNish   +2 more
core   +1 more source

Differential Genetic and Epigenetic Regulation of Catechol-O-Methyl-Transferase (COMT) is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder

Frontiers in Behavioral Neuroscience, 2013
The catechol-O-methyltransferase (COMT) enzyme is critical for the catabolic regulation of synaptic dopamine, resulting in altered cortical functioning.
Seth Davin Norrholm, Tanja eJovanovic, Alicia eSmith, Elisabeth B Binder, Elisabeth B Binder, Torsten eKlengel, Karen eConneely, Kristina B. Mercer, Jennifer S. Davis, Kimberly eKerley, Jennifer A. Winkler, Charles F. Gillespie, Bekh eBradley, Kerry J Ressler   +13 more
doaj   +1 more source

Social instability stress differentially affects amygdalar neuron adaptations and memory performance in adolescent and adult rats

Frontiers in Behavioral Neuroscience, 2014
Adolescence is a time of developmental changes and reorganization in the brain. It has been hypothesized that stress has a greater neurological impact on adolescents than on adults.
Sheng-Feng eTsai, Sheng-Feng eTsai, Tung-Yi eHuang, Chia-Yuan eChang, Chia-Yuan eChang, Yuan-Chang eHsu, Shean-Jen eChen, Shean-Jen eChen, Lung eYu, Lung eYu, Yu-Min eKuo, Yu-Min eKuo, Chauying J. Jen, Chauying J. Jen   +13 more
doaj   +1 more source

CB2 cannabinoid receptor expression is increased in 129S1/SvImJ mice: behavioral consequences

Frontiers in Pharmacology, 2022
Genetic and environmental factors are implicated in the etiology of neuropsychiatric diseases. Inbred mouse strains, including the 129S1/SvImJ (S1), constitute important models to study the influence of genetic factors in these conditions.
Marc Ten-Blanco, Inmaculada Pereda-Pérez, Cristina Izquierdo-Luengo, Fernando Berrendero   +3 more
doaj   +1 more source

Battery‐Inspired Electrochemical Synapses for Neuromorphic Applications

Advanced Science, EarlyView.
Battery‐ion‐inspired synaptic devices integrate diverse electrolyte systems (solid, ion‐gel, liquid) with transition metal oxides, two‐dimensional materials, and organic channels to regulate ion‐electron coupling. By tailoring ion transport and host interactions, these platforms enable controllable plasticity and energy‐efficient implementations for ...
Won Woo Lee, SeongCheol Jang, Wangmyung Choi, Jaewon Park, Jaehyun Hur, Hocheon Yoo, Hyun‐Suk Kim   +6 more
wiley   +1 more source

Pre-Learning Stress That Is Temporally Removed from Acquisition Impairs Fear Learning

Biology, 2023
Few studies have examined the time-dependent effects of stress on fear learning. Previously, we found that stress immediately before fear conditioning enhanced fear learning.
Phillip R. Zoladz, Chloe N. Cordes, Jordan N. Weiser, Kassidy E. Reneau, Kayla M. Boaz, Sara J. Helwig, Emma M. Virden, Caitlin K. Thebeault, Cassidy L. Pfister, Bruktawit A. Getnet, Taylor D. Niese, Sydney L. Parker, Mercedes L. Stanek, Kristen E. Long, Seth D. Norrholm, Boyd R. Rorabaugh   +15 more
doaj   +1 more source

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

Advanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang, Jiachen Wang, Taozhi Wang, Yanling Li, Youyi Zhao, Guanghui Hao, Peiqin Gong, Ruling Chen, Yilin Fang, Shengxi Wu, Haopeng Zhang, Hui Zhang   +11 more
wiley   +1 more source

In Your Face: Startle to Emotional Facial Expressions Depends on Face Direction

i-Perception, 2017
Although faces are often included in the broad category of emotional visual stimuli, the affective impact of different facial expressions is not well documented.
Ole Åsli, Henriette Michalsen, Morten Øvervoll   +2 more
doaj   +1 more source

Adolescent Vulnerability to Heightened Emotional Reactivity and Anxiety After Brief Exposure to an Obesogenic Diet

Frontiers in Neuroscience, 2020
BackgroundEmerging evidence demonstrates that diet-induced obesity disrupts corticolimbic circuits underlying emotional regulation. Studies directed at understanding how obesity alters brain and behavior are easily confounded by a myriad of complications
Julio D. Vega-Torres, Matine Azadian, Raul A. Rios-Orsini, Arsenio L. Reyes-Rivera, Perla Ontiveros-Angel, Johnny D. Figueroa   +5 more
doaj   +1 more source