Generalization of Fear-potentiated Startle in the Presence of Auditory Cues: A Parametric Analysis [PDF]
Frontiers in Behavioral Neuroscience, 2014 Intense fear responses observed in trauma-, stressor-, and anxiety-related disorders can be elicited by a wide range of stimuli similar to those that were present during the traumatic event. The present study investigated the experimental utility of fear-
Seth Davin Norrholm +9 more
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Beyond Extinction: Prolonged Conditioning and Repeated Threat Exposure Abolish Contextual Renewal of Fear-Potentiated Startle Discrimination but Leave Expectancy Ratings Intact [PDF]
Frontiers in Psychiatry, 2018 Extinction treatments decrease fear via repeated exposures to the conditioned stimulus (CS) and are associated with a return of fear. Alternatively, fear can be reduced via reductions in the perceived intensity of the unconditioned stimulus (US), e.g ...
Arne Leer, Kim Haesen, Bram Vervliet
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Prospective Associations between Emotion Dysregulation and Fear-Potentiated Startle: The Moderating Effect of Respiratory Sinus Arrhythmia [PDF]
Frontiers in Psychology, 2016 Background: Emotion dysregulation has been implicated in the negative outcomes following trauma exposure. A proposed biomarker of emotion dysregulation, respiratory sinus arrhythmia (RSA), has demonstrated associations with trauma-related phenomena, such
Antonia Victoria Seligowski +6 more
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No impact of deep brain stimulation on fear-potentiated startle in obsessive-compulsive disorder [PDF]
Frontiers in Behavioral Neuroscience, 2014 Deep brain stimulation (DBS) of the ventral internal capsule is effective in treating therapy refractory obsessive-compulsive disorder (OCD). Given the close proximity of the stimulation site to the stria terminalis (BNST), we hypothesized that the ...
Johanna M.P. Baas +9 more
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The effects of spaced versus massed extinction training on extinction retention of conditioned fear learning in male rats [PDF]
Frontiers in Behavioral NeuroscienceIntroductionExtinction learning of conditioned fear behavior has been used as a translational model to study human fear-, anxiety-, trauma-, and stressor-related disorders and their underlying neurobiology in animal models because the underlying neural ...
Grant W. LeVasseur +4 more
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The role of fear learning in the development of psychosis: an EEG study utilizing a differential fear conditioning paradigm in people with psychotic vulnerability [PDF]
SchizophreniaBy studying how individuals in an “at-risk” state of psychosis learn about threat and safety cues – specifically, how they develop and unlearn fear responses to neutral cues – we might better understand the mechanisms leading to heightened arousal and ...
Metin Özyagcilar +4 more
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Characterizing the Prevalence of Psychiatric Conditions and Fear-Potentiated Startle Response in Civilians with a History of Trauma and Seizures [PDF]
Chronic StressBackground Depression, posttraumatic stress disorder (PTSD), and suicidality are more prevalent among people with seizures, but few studies exist in low-resourced minoritized populations.
Trinidi Prochaska +8 more
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Maternal buffering of fear-potentiated startle in children and adolescents with trauma exposure [PDF]
Social Neuroscience, 2017 Sanne J H van Rooij +2 more
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Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt [PDF]
Journal of Affective Disorders, 2014 Elizabeth Ballard +2 more
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Anxiety, fear extinction, and threat-related amygdala reactivity in children exposed to urban trauma
Journal of Experimental Psychopathology, 2022 Introduction Childhood trauma is strongly associated with fear-related psychopathology, like anxiety and posttraumatic stress disorder (PTSD). Atypical fear extinction and neural responses to social threat (i.e., negative emotional faces) may serve as ...
John M. France BS +12 more
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