Results 1 to 10 of about 480,216 (163)
Neural Plasticity, 2002 Ascending 5-HT projections from the median raphe nucleus (MRN), probably to the hippocampus, are implicated in the acquisition of contextual fear (background stimuli), as assessed by freezing behavior.
R. C. B. Silva +4 more
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Versatility of Fear-potentiated Startle Paradigms for Assessing Human Conditioned Fear Extinction and Return of Fear [PDF]
Frontiers in Behavioral Neuroscience, 2011 Fear conditioning methodologies have often been employed as testable models for assessing learned fear responses in individuals with anxiety disorders such as post-traumatic stress disorder (PTSD) and specific phobia.
Seth Davin Norrholm +12 more
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Generalization of Fear-potentiated Startle in the Presence of Auditory Cues: A Parametric Analysis [PDF]
Frontiers in Behavioral Neuroscience, 2014 Intense fear responses observed in trauma-, stressor-, and anxiety-related disorders can be elicited by a wide range of stimuli similar to those that were present during the traumatic event. The present study investigated the experimental utility of fear-
Seth Davin Norrholm +9 more
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Contextual fear conditioning in virtual reality is affected by 5HTTLPR and NPSR1 polymorphisms: effects on fear-potentiated startle [PDF]
Frontiers in Behavioral Neuroscience, 2013 The serotonin (5-HT) and neuropeptide S (NPS) systems are discussed as important genetic modulators of fear and sustained anxiety contributing to the etiology of anxiety disorders.
Evelyn eGlotzbach-Schoon +10 more
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Anxiety, fear extinction, and threat-related amygdala reactivity in children exposed to urban trauma
Journal of Experimental Psychopathology, 2022 Introduction Childhood trauma is strongly associated with fear-related psychopathology, like anxiety and posttraumatic stress disorder (PTSD). Atypical fear extinction and neural responses to social threat (i.e., negative emotional faces) may serve as ...
John M. France BS +12 more
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Brain Sciences, 2022 Childhood maltreatment may alter fear neurocircuitry, which results in pathological anxiety and depression. One alteration of fear-related behaviors that has been observed in several psychiatric populations is an overgeneralization of fear.
Phillip Zoladz +15 more
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Behavioral Expression of Contextual Fear in Male and Female Rats
Frontiers in Behavioral Neuroscience, 2021 The study of fear conditioning has led to a better understanding of fear and anxiety-based disorders such as post-traumatic stress disorder (PTSD). Despite the fact many of these disorders are more common in women than in men, the vast majority of work ...
Amanda S. Russo, Ryan G. Parsons
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Dopamine D2-like receptors modulate unconditioned fear: role of the inferior colliculus. [PDF]
PLoS ONE, 2014 BACKGROUND: A reduction of dopamine release or D2 receptor blockade in the terminal fields of the mesolimbic system clearly reduces conditioned fear.
Amanda Ribeiro de Oliveira +4 more
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Blood pressure variations real-time reflect the conditioned fear learning and memory. [PDF]
PLoS ONE, 2012 The conditioned fear learning and memory occurs when a neutral conditioned stimulus (CS) is paired with an aversive unconditioned stimulus (US). This process is critically dependent on the amygdala and inevitably involves blood pressure (BP) alterations.
Yuan-Chang Hsu +5 more
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Frontiers in Psychology, 2016 Although impaired fear extinction has repeatedly been demonstrated in patients with anxiety disorders, little is known about whether these impairments persist after treatment.
Puck eDuits +7 more
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