Results 51 to 60 of about 3,343,046 (404)

An Adaptive Management Model for Brown Bears in Hokkaido: Based on Total Population and the Number of Nuisance Bears

open access: yesPopulation Ecology, EarlyView.
Bear management changes management actions according to the horizontal axis of the population size and the vertical axis of the number of nuisance bears. Aiming for the target population size of Ntar, Actions I and II protect the bears, and Action IV reduces the population.
Hiroyuki Matsuda   +5 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

“You made it, you take care of it”: Data Management as Personal Information Management

open access: yesInternational Journal of Digital Curation, 2011
This study explores how researchers at a major Midwestern university are managing their data, as well as the factors that have shaped their practices and those that motivate or inhibit changes to that practice.
Kathleen Fear
doaj   +6 more sources

Novel Presentation to a Rare Disease: Refractory Seizures Caused by Rosai–Dorfman Disease

open access: yesAnnals of Internal Medicine: Clinical Cases
Rosai–Dorfman disease (RDD) is a non-Langerhans lymphoproliferative disorder that is defined by sinus histiocytosis with massive lymphadenopathy. It can present with a wide spectrum of clinical presentations depending on the organ systems affected ...
Shoon L. Oo   +3 more
doaj   +1 more source

Śāntideva and the moral psychology of fear [PDF]

open access: yes, 2019
Buddhists consider fear to be a root of suffering. In Chapters 2 and 7 of the Bodhicaryāvatāra, Śāntideva provides a series of provocative verses aimed at inciting fear to motivate taking refuge in the Bodhisattvas and thereby achieve fearlessness.
Finnigan, Bronwyn
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Synergism between two BLA-to-BNST pathways for appropriate expression of anxiety-like behaviors in male mice

open access: yesNature Communications
Understanding how distinct functional circuits are coordinated to fine-tune mood and behavior is of fundamental importance. Here, we observe that within the dense projections from basolateral amygdala (BLA) to bed nucleus of stria terminalis (BNST ...
Ren-Wen Han   +4 more
doaj   +1 more source

Pre- and pro-biotics may improve mineral absorption and retention in the growing male rat : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Science in Nutritional Science at Massey University, Turitea, Palmerston North, New Zealand [PDF]

open access: yes, 2005
Probiotics are bacteria, which reside in the large intestine and concur beneficial health effects on their host. Their abundance can be selectively-stimulated by prebiotics, such as fructo-oligosaccharide (FOS); prebiotics are oligosaccharides, which are
Fear, Alison Lindsay
core  

Watch Out for the Beast: Fear Information and Attentional Bias in Children [PDF]

open access: yes, 2006
Although valenced information about novel animals changes the implicit and explicit fear beliefs of children (Field & Lawson, 2003), how it might lead to anxiety is unknown.
Andy P. Field   +4 more
core   +1 more source

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