Results 61 to 70 of about 1,068,363 (285)
iLIVERBackground and aims: Frailty predicts death in advanced cirrhosis and among transplant candidates, but whether a frailty-like functional index identifies mortality risk in the far larger population of community-dwelling adults with liver disease, who are
Chukwuemeka E. Ogbu +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
British ship passing under the Cape Fear Memorial Bridge
, 1986 British ship passing under the Cape Fear Memorial Bridge in ...
core +5 more sources
Alternative uses for tannery wastes: a review of environmental, sustainability, and science
Journal of Leather Science and Engineering, 2020 The manufacture of leather covers a wide productive chain and beyond contributes to the economic flow. The various stages of leather processing result in high volumes of solid waste.
Cesar Vinicius Toniciolli Rigueto +6 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Reproduction of a photograph of the Cape Fear Ford dealership near Market Street and Second Street in downtown Wilmington.
core +2 more sources
Social isolation and loneliness: an integration framework for medical education
Frontiers in MedicineLoneliness and social isolation are increasingly recognized as critical public health issues, linked to adverse outcomes such as cardiovascular disease, cognitive decline, depression, and increased healthcare utilization.
Jerlinda G. C. Ross +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source